眼内液病原学检测的研究进展

Research on examination of intraocular fluid for diagnosis of infectious ocular diseases

包括病毒性视网膜炎、眼内炎和眼弓形虫病等在内的感染性眼病，是临床常见的致盲眼病。传统血清学检查很难在这些疾病的诊断和治疗方面提供帮助，甚至可能造成误导。检测包括房水和玻璃体液在内的眼内液中病原微生物的核酸、抗体和细胞因子，可为临床提供眼内局部病原和免疫反应信息，有助于快速诊断。本文就眼内液病原学检测的最新研究进展进行总结和分析，以期为临床工作提供参考。

Including viral retinitis, endophthalmitis and ocular toxoplasmosis etc, Infectious ocular diseases, which include viral retinitis, endophthalmitis and ocular toxoplasmosis etc, are the common causes leading to blindness. Traditional examinations of serum are of limited help in diagnosing these diseases and are sometimes misleading. Examinations of pathogen DNA, antibodies and cytokines in the intraocular fluids including aqueous humor and vitreous humor can help clinicians get in situ information and hereby confirm diagnosis rapidly,（ Chin J Ophthalmol, 2018, 54： 551-556）