针刺联合氟桂利嗪、尼莫地平治疗偏头痛临床分析

Clinical Analysis of Acupuncture, Flunarizine and Nimodipine in Treatment of Migraine

目的探讨针刺联合氟桂利嗪、尼莫地平治疗偏头痛的临床效果,进一步指导临床。方法便利选取2016年1月—2017年10月黑龙江省中医药科学院该针灸科门诊治疗的120例患者按照随机原则分为治疗组和对照组两组,每组60例,对照组给予常规西药治疗,治疗组在对照组基础上结合普通针刺治疗,比较两组患者的临床疗效,治疗前后疾病发作情况、疼痛程度及不良反应情况。结果治疗组临床痊愈25例,显效18例,有效14例,无效3例,总有效率为95.0%,对照组临床痊愈10例,显效20例,有效18例,无效12例,总有效率为80.0%,治疗组临床治疗效果明显优于对照组,两组比较差异有统计学意义(P<0.05),两组治疗前疾病发作频率、每次发作持续时间比较差异无统计学意义(P>0.05),治疗后两组疾病发作频率、每次发作持续时间比较差异有统计学意义(P<0.05),治疗后两组视觉疼痛模拟评分(VAS)均较治疗前有所改善,治疗组优于对照组(P<0.05),两组不良反应情况差异无统计学意义(P>0.05)。结论针刺联合氟桂利嗪、尼莫地平治疗偏头痛的临床效果满意。

Objective To study the clinical effect of acupuncture, flunarizine and nimodipine in treatment of migraine for further clinical guidance. Methods 120 cases of outpatients in our hospital from January 2016 to October 2017 were convenient selected and randomly divided into two groups with 60 cases in each, the control group used the routine western medicine, while the treatment group used the common acupuncture on the basis of the control group, and the clinical curative effect, attack of diseases, pain degree and adverse reactions were compared between the two groups. Results In the treatment group, 25 cases were cured, 18 cases were markedly effective, and 14 cases were effective, 3 cases were ineffective, and the total effective rate was 95.0%, in the control group, 10 cases were cured, 20 cases were markedly effective, 18 cases were effectively, 12 cases were ineffective and the total effective rate was 80.0%, and the treatment effect in the treatment group was obviously better than that in the control group, and the difference between the two groups was statistically significant, P〈0.05, before treatment, the differences in the attack frequency of diseases, each attack duration between the two groups were not statistically significant（P〉0.05）, after treatment, the differences in the attack frequency, and each attack duration between the two groups were statistically significant（P〈0.05）, after treatment, the VAS was improved compared with that before treatment, and the VAS in the treatment group was better than that in the control group,the difference was statistically significant（P〈0.05）, and there was no obvious difference in the adverse reaction between the two groups（P〉0.05）. Conclusion The clinical effect of acupuncture, flunarizine and nimodipine in treatment of migraine is satisfactory.