380例呼吸道感染患儿肺炎支原体检测结果分析

Analysis of mycoplasma pneumoniae detection in 380 children with respiratory tract infections

目的分析呼吸道感染患儿肺炎支原体(MP)感染的分布特征,为临床防治提供有效依据。方法回顾性分析安徽医科大学第一附属医院2017年1~12月收治的呼吸道感染患儿380例临床资料,所有患儿均采用间接免疫荧光法检测了肺炎支原体(MP)Ig M,统计分析呼吸道感染患儿MP阳性率及MP感染患儿年龄、性别及季节性分布。结果 380例呼吸道感染患儿中MP-Ig M阳性148例,MP阳性率为38.95%;其中女患儿阳性率44.86%高于男患儿31.33%,差异有统计学意义(P<0.05);MP感染患儿中,学龄前组患儿阳性率最高为58.54%,婴儿组患儿阳性率最低为8.33%,差异有统计学意义(P<0.05);春夏季MP阳性率高于秋冬季,差异有统计学意义(P<0.05),其中5月份检出阳性率最高,为58.53%。结论 MP是引起儿童呼吸道感染的重要病原体,呼吸道感染患儿MP感染女性多于男性、以学龄前患儿多见、好发于春夏季。

Objective To analyze the distribution characteristics of mycoplasma pneumoniae（ MP） infection in those children with respiratory tract infections,and provide reliable evidence for clinical prevention and treatment. Methods The clinical data of 380 children with respiratory tract infections ever treated in our hospital between Jan 2017 and Dec were retrospectively analyzed. After MP-Ig M detection in all children by indirect immunofluorescence assay,the positive rate of MP in these children and the distribution features of age,gender and season in the infected children were then calculated and analyzed. Results Among the 380 cases with respiratory tract infections,148 cases were found to be MP-Ig M positive and the positive rate of MP was 38. 95%. Meanwhile,the positive rate of 44. 86% in girls was significantly higher than the positive rate of 31. 33% in boys（ P〈0. 05）. Among those MP infected children,the highest positive rate of 58. 54%was found in preschool children,and the lowest positive rate of 8. 33% was found in infants,with significant difference between them（ P〈0. 05）. The positive rate of MP in spring and summer was significantly higher than that in autumn and winter（ P〈0. 05）,in which the positive rates of 58. 53% in May being the highest. Conclusion s MP has been the important pathogen of respiratory tract infections in children. In respiratory tract infections,the MP infection would be more common in girls,in preschool children,and in spring and summer.