麻杏薏甘汤治疗慢性湿疹临床观察

Clinical Observation of Using Maxing Yigan Decoction in the Treatment of Chronic Eczema

目的:观察麻杏薏甘汤治疗慢性湿疹的临床疗效。方法:将96例慢性湿疹患者随机分为两组,每组48例,对照组外涂卤米松乳膏治疗,观察组予以麻杏薏甘汤内服治疗,两组均以7天为1个疗程,共治疗3个疗程,比较两组临床疗效。结果:治疗3个疗程,观察组总有效率为95.83%,明显高于对照组的83.33%(P<0.05);两组皮肤瘙痒程度评分较治疗前显著降低(P<0.05),且观察组降低幅度大于对照组(P<0.05);两组皮肤病生活质量指数(DLQL)评分较治疗前显著降低(P<0.05),且观察组降低幅度大于对照组(P<0.05);两组治疗期间均未发现与药物有关的严重不良反应,仅对照组出现局部毛囊炎样皮疹1例(2.08%),不影响正常治疗。结论:麻杏薏甘汤治疗慢性湿疹疗效确切,不良反应少,复发率低,值得临床推广。

Objective： To observe the clinical efficacy of using Maxing Yigan Decoction in the treatment of chronic eczema.Methods： 96 cases of patients with chronic eczema were randomly divided into two groups（ each n = 48）. The controlled group was treated with external application of halometasone cream,and the observation group was given Maing Yigan Decoction orally,and the two groups were treated for 3 courses with 7 days for a course. The clinical efficacy was compared between the two groups. Results： After 3 courses of treatment,the total effective rate in the observation group was significantly higher than that in the controlled group（ 95. 83% vs 83. 33%）（ P〈0. 05）. The score of pruritus in the two groups was significantly lower than that before treatment（ P〈0. 05）,and the reduction in the observation group was greater than that in the controlled group（ P〈0. 05）. The dermatology life quality index（ DLQL） score in the two groups was significantly lower than that before treatment（ P〈0. 05）,and the decrease in the observation group was higher than that in the controlled group（ P〈0. 05）. No serious drug-related adverse reactions were found during treatment,and there was only 1 case（ 2. 08%） of local folliculitis-like rash in the controlled group but it did not affect normal treatment. Conclusions： Maxing Yigan Decoction has exact efficacy in treating chronic eczema,and it has few adverse reactions and low recurrence rate,therefore it is worthy of clinical promotion.