摘要
利用介孔分子筛MCM-41固载磷钨酸作为非均相催化剂,在水相中,简单高效地催化亚胺和丙二腈进行亲核加成-消去反应,合成了一系列的苄烯丙二腈化合物,产率最高可达99%.该方法具有操作简单、环境友好、底物普适性好、产率高和催化剂可回收再利用等优点,为碳-碳键的构筑提供了一种新的方法.
A convenient and excellent yield procedure for the preparation of benzylidenemalononitrile by addition-elimination reaction of imine with malonitrile in the presence of immobilized H3PW12O40 as heterogeneous catalyst in water is described, and a variety of the corresponding products were obtained in high yield （up to 99%）. The approach was characterized by simple operation, environment friendly, excellent yields and the catalyst was found to exhibit better recyclability. It provides a new method for the carbon-carbon bond formation in organic synthesis.
作者
侯亚东
董秀芝
杨超
惠永海
解正峰
Hou Yadong;Dong Xiuzhi;Yang Chao;Hui Yonghai;Xie Zhengfeng(Key Laboratory of Oil ＆ Gas Fine Chemicals,Ministry of Education ＆ Xinjiang Uyghur Autonomous Region,College of Chemistry and Chemical Engineering,Xinjiang University,Urumqi 830046;School of Chemistry and Chemistry Engineering,Lingnan Normal University,Zhanjiang 524048;School of Chemistry and Chemistry Engineering,Southwest Petroleum University,Chengdu 610500)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2018年第7期1749-1754,共6页
Chinese Journal of Organic Chemistry
基金
国家自然科学基金(Nos.21362036
51564045)资助项目~~
