摘要
从中药南鹤虱(Fructus carotae)中分离纯化得到7个倍半萜类化合物,分别鉴定为7-ethoxy-4(15)-oppositen-1β-ol(1),11-乙酰氧基-8β-当归酰氧基-15-甲氧基-4α,5α-环氧愈创木烷-3-酮(2),11-乙酰氧基-8β-丙酰氧基-4-愈创木烯-3-酮(3),1-oxo-5α,7αH-eudesma-3-en-15-al(4),1β-hydroxy-4(15),7-eudesmadiene(5),1β-hydroxy-4(15),5E,10(14)-germacratriene(6),1β-hydroxy-4(15),5-eudesmadiene(7).其中化合物1和2为新的化合物,新化合物的结构进一步通过HR-ESIMS,1D NMR和2D NMR等光谱技术确定.
Seven sesquterpenoids were obtained from the Chinese traditional medicine, Fructus carotae, and their structures were identified as 7-ethoxy-4(15)-oppositen-1β-ol (1), 11-acetoxy-8β-angeloyloxy-15-methoxy-4α,5α-epoxyarbutane-3-one (2), 11-acetoxy-8β-propionyl-4-guaien-3-one (3), 1-oxo-5α,7αH-eudesma-3-en-15-al (4), 1β-hydroxy-4(15),7-eudesmadiene (5), 1β-hydroxy-4(15),5E,10(14)-germacratriene (6) and 1β-hydroxy-4(15),5-eudesmadiene (7). Compounds 1 and 2 were new sesquterpenoid compounds, and their structures were determined by the analysis of HR-ESIMS, 1D NMR and 2D NMR.
作者
成蕾
刘贵园
潘胤池
张茂生
肖世基
Cheng Lei;Liu Guiyuan;Pan Yinchi;Zhang Maosheng;Xiao Shiji(School of Pharmacy,Zunyi Medical University,Zunyi 56300)
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2018年第7期1829-1832,共4页
Chinese Journal of Organic Chemistry
基金
Project supported by the National Natural Science Foundation of China(No.31560102)~~