氯吡格雷对冠心病的治疗效果及不良反应评价

Clopidogrel in the Treatment of Coronary Heart Disease and Adverse Reactions

目的在临床上,研究对冠心病患者采取氯吡格雷的方案进行治疗后的价值。方法选取该院冠心病患者,例数合计为200例,选取时间范围是2014年5月—2017年5月,将其依据随机数字表法原则分2组,100例为一组。一组给予常规药物为主治疗(称为:对照组),另一组使用氯吡格雷(称为:观察组),对比2组治疗的效果,发生的不良反应状况,并记录2组的凝血指标治疗前后变化。结果观察组冠心病患者的总有效率数据高达92.00%,明显高于对照组,2组的数据(92.00%VS 72.00%)存在强烈的比对性(χ~2=6.856,P<0.05)。观察组冠心病患者的总不良反应概率为(3.00%),和对照组的指标情况(5.00%)相比,差异无统计学意义(χ~2=5.210,P>0.05)。结论针对冠心病患者实施氯吡格雷的方案治疗,其效果理想。

Objective This paper tries to study the clinical value of clopidogrel in patients with coronary heart disease（CHD） after treatment. Methods A total of 200 patients with coronary heart disease were enrolled in this study from May 2014 to May 2017 and were divided into 2 groups according to the principle of random number table. One group treated with conventional drugs as the control group, the other with clopidogrel as observation group, compared the effect of two groups of treatment, the occurrence of adverse reactions, and recorded two groups of coagulation index changes before and after treatment. Results The total effective data of patients with coronary heart disease was 92.00%,significantly higher than that in the control group, there were significant difference between the two groups of（92.00%vs 72.00%）,（cm^2=6.856, P〈0.05）. The total adverse reaction probability of patients with coronary heart disease was（3.00%）, compared with the control group（5.00%）, the difference was not significant（cm^2=5.210, P〉0.05）. Conclusion Clopidogrel for the treatment of patients with coronary heart disease program, the effect is ideal.