瓜蒌瞿麦丸合氯沙坦对糖尿病肾病早期尿微量白蛋白影响的研究

Study on Effect of Trichosanis Pills and Losartan on the Early Microalbuminuria of Diabetic Nephropathy

目的研究瓜蒌瞿麦丸联合氯沙坦治疗糖尿病肾病早期微量白蛋白的临床效果如何。方法选取该院2016年5月—2017年5月诊断为糖尿病肾病患者共80例,将其随机分为研究组40例(应用瓜蒌瞿麦丸+氯沙坦治疗)及对照组40例(应用氯沙坦治疗),研究两组患者经过治疗前后的尿微量白蛋白的变化情况怎样。结果研究组治疗前后尿微量白蛋白(160.18±7.34)、(102.34±8.56)mg/L低于对照组(161.23±8.12)、(139.45±8.41)mg/L,差异有统计学意义(P<0.05)。结论瓜蒌瞿麦丸联合氯沙坦治疗方法可以显著的降低糖尿病肾病患者的微量白蛋白的排出量。

Objective To research the clinical effect of trichosanis pills and losartan on the early microalbuminuria of diabetic nephropathy. Methods 80 cases of patients with diabetic nephropathy diagnosed in our hospital from May2016 to May 2017 and randomly divided into two groups with 40 cases in each, the research group were treated with trichosanis pills and losartan, while the control group were treated with losartan, and the changes of microalbuminuria before and after treatment of the two groups were studied. Results The microalbuminuria before and after treatment in the research group were lower than that in the control group（160.18±7.34）mg/L,（102.34±8.56）mg/L vs（161.23±8.12）mg/L,（139.45±8.41）mg/L, with statistical significance（P〈0.05）. Conclusion The trichosanis pills and losartan can obviously decrease the discharge of microalbuminuria of patients with diabetic nephropathy.