药物联合鼻腔冲洗在鼻部疾病引起的儿童上气道咳嗽综合征中的应用研究

Application Research of Drugs Combined with Nasal Irrigation in Children's Upper Airway Cough Syndrome Caused by Nasal Diseases

目的探讨和分析药物联合鼻腔冲洗在鼻部疾病引起的儿童上气道咳嗽综合征中的应用效果。方法选取该院2016年10月—2017年9月在该院儿科等科室进行诊疗的患儿240例确定为分析对象,按照随机原则分成观察组和对照组,对于对照组患儿,采用采取的是糠酸莫米松鼻喷剂(即鼻用糖皮质激素),在晨间喷鼻1次/d,200μg/次,持续给药3个月;对于观察组患儿,在对照组治疗的基础上,另外实施鼻腔冲洗,治疗3个月后,对于两组的治疗效果进行对比。结果经过3个月治疗,观察组的治愈率为70.8%,显著高于对照组(47.5%),两组疗效对比差异有统计学意义(χ~2=11.307,P<0.05)。结论对于UACS导致的慢性咳嗽患儿,在采取药物喷鼻配合鼻腔冲洗,来实施治疗后,能够取得理想疗效,值得临床推广。

Objective To study and analyze the application effect of drugs combined with nasal irrigation in children＇s upper airway cough syndrome caused by nasal diseases. Methods 240 cases of children diagnosed and treated in our hospital from October 2016 to September 2017 were selected and randomly divided into two groups, the control group were treated with mometasone furoate nasal spray（namely nasal glucocorticoid）, 1 time/d in the morning, 200 μg/times,and the continuous administration was three months, the patients in the observation group used the nasal irrigation on the basis of the control group, after three months, the treatment effect was compared between the two groups. Results After three-month treatment, the cure rate in the observation group was obviously higher than that in the control group,（70.8% vs 47.5%）, and the difference in the curative effect between the two groups was statistical significance（χ2=11.307, P 〈0.05）. Conclusion The drugs combined with nasal irrigation in children＇s upper airway cough syndrome caused by nasal diseases can produce an ideal curative effect, and it is worth clinical promotion.