阿司匹林联合丁苯酞软胶囊治疗急性脑梗死的临床效果

Clinical effect of aspirin and butylphthalide soft capsule in the treatment of acute cerebral infarction

目的评价阿司匹林联合丁苯酞软胶囊治疗急性脑梗死的临床效果。方法选取我院收治的95例急性脑梗死患者,根据随机数字法将其分为观察组(n=47)和对照组(n=48)。对照组予以阿司匹林治疗,观察组在对照组的基础上予以丁苯酞软胶囊联合治疗。比较两组的治疗效果、认知功能及NIHSS评分。结果观察组的治疗总有效率明显高于对照组(P<0.05)。治疗后,两组的QCST-E量表各维度评分均升高,且除动作指令外,观察组的其他各维度评分均高于对照组(P<0.05)。两组治疗第7天及治疗第14天的NIHSS评分均低于治疗前,两组治疗第14天的NIHSS评分均低于治疗第7天,且观察组低于对照组(P<0.05)。结论阿司匹林联合丁苯酞软胶囊可有效改善急性脑梗死患者的神经功能、认知功能,值得借鉴。

Objective To evaluate the clinical effect of aspirin combi ned with butylphthalide soft capsule in the treatment of acute cerebral infarction. Methods A total of 95 patients with acute cerebral infarction admitted in our hospital were divided into observation group（n=47） and control group（n=48） according to the random number method. The control group was treated with aspirin, and the observation group was treated with butylphthalide soft capsule based on the control group. The treatment effects, cognitive function and NIHSS scores of the two groups were compared. Results The total effective rate of treatment in the observation group was significantly higher than that in the control group（P〈0.05）. After treatment, each dimension score of QCST-E scale in both groups increased; except for the movement instructions, the scores of other dimensions in the observation group were higher than those in the control group（P〈0.05）. The NIHSS scores on the 7 th and the 14 th day of treatment in both groups were lower than those before treatment（P〈0.05）. The NIHSS scores on the 14 th day of the two groups were lower than those of the 7 th day of treatment, and those of the observation group were lower than the control group（P〈0.05）. Conclusion Aspirin combined with butylphthalide soft capsule can effectively improve the neurological function and cognitive function in patients with acute cerebral infarction, which is worth learning.