健康体检者血脂及血尿酸水平及同糖尿病发生的相关性分析

Analysis of Correlation between the Blood Liquid and Blood Uric Acid Levels and Occurrence of Diabetes

目的探讨健康体检者血脂及血尿酸水平同糖尿病发生的相关性。方法将2015年8月—2017年8月期间该院收治的150例糖尿病患者作为观察组,同期150名健康体检者作为对照组,均使用生化分析仪对血脂及血尿酸各指标进行检测,进而比较两组血清尿酸、总胆固醇和三酰甘油水平的差异。结果 (1)观察组的总胆固醇(5.21±1.11)mmol/L、低密度脂蛋白胆固醇(3.02±1.55)mmol/L、三酰甘油(2.41±1.14)mmol/L以及血尿酸(333.25±55.41)mmol/L均高于对照组的总胆固醇(3.54±1.22)mmol/L、低密度脂蛋白胆固醇(2.88±1.21)mmol/L、三酰甘油(1.33±0.11)mmol/L以及血尿酸(258.89±162.58)mmol/L,两组数据均值差异有统计学意义(Z=5.590,6.926,4.892,2.739,P<0.05);(2)观察组的高密度脂蛋白胆固醇(1.26±1.55)mmol/L则小于对照组高密度脂蛋白胆固醇(2.68±1.21)mmol/L,差异有统计学意义(Z=-3.393,P<0.05);(3)糖尿病中血脂异常组的总胆固醇(4.31±1.21)mmol/L、高密度脂蛋白胆固醇(1.24±1.35)mmol/L、低密度脂蛋白胆固醇(3.32±1.47)mmol/L、三酰甘油(2.01±1.24)mmol/L以及血尿酸(353.25±52.41)mmol/L均高于对照组的总胆固醇(3.12±1.52)mmol/L、高密度脂蛋白胆固醇(0.68±0.21)mmol/L/L、低密度脂蛋白胆固醇(2.46±1.01)mmol/L、三酰甘油(1.43±0.21)mmol/L以及血尿酸(278.62±154.44)μmol/L,两组数据比较差异有统计学意义(Z=5.190,1.093,6.946,4.392,2.239,P<0.05)。结论对糖尿病患者进行检查后发现,糖尿病患者多合并脂质代谢异常,高胆固醇和高三酰甘油血症发生率均高于健康人群,因此为了促进患者的身体健康,需要做好患者血糖和血脂方面的控制工作,具有重要的临床意义。

Objective To study the correlation between the blood liquid and blood uric acid levels and occurrence of diabetes. Methods 150 cases of diabetes patients admitted and treated in our hospital from August 2015 to August2017 were selected as the observation group, 150 cases of healthy physical examination people were selected as the control group, and the blood liquid and blood uric acid levels were tested by the biochemical analysis, and the differences in the serum blood uric, total cholesterol and three acyl glycerol levels were compared between the two groups.Results The total cholesterol, low density lipoprotein cholesterol, triacylglycerol and blood uric acid were higher than those in the control group[（5.21±1.11）mmol/L,（3.02±1.55）mmol/L,（2.41±1.14）mmol/L,（333.25±55.41）mmol/L vs（ 3.54±1.22）mmol/L,（ 2.88±1.21）mmol/L,（1.33 ±0.11） mmol/L,（258.89 ±162.58） mmol/L], and the differences between groups were statistically significant（Z =5.590,6.926,4.892,2.739,P〈0.05）, and the high density lipoprotein cholesterol in the observation group was lower than that in the control group, [（1.26±1.55） mmol/L vs（2.68±1.21） mmol/L], and the difference was statistically significant（Z=-3.393, P〈0.05）, and the total cholesterol, high density lipoprotein cholesterol,low density lipoprotein cholesterol, triacylglycerol and blood uric acid in the abnormal blood liquid group were higher than those in the control group [（4.31 ±1.21）mmol/L,（1.24 ±1.35）mmol/L,（3.32 ±1.47）mmol/L,（2.01 ±1.24）mmol/L,（353.25±52.41）mmol/L vs（ 3.12±1.52）mmol/L,（0.68±0.21）mmol/L,（2.46±1.01）mmol/L,（1.43±0.21）mmol/L,（278.62±154.44）μmol/L], and the differences were obvious, with statistical significance（Z=5.190, 1.093, 6.946, 4.392, 2.239,P〈0.05）. Conclusion The incidence rates of hypercholesterolemia and hypertriglyceridemia are higher than those of the healthy group for patients with diabetes combined with abnormal lipids metabolism, therefore, in order to promote the physical health, we need to do well in the control work of blood glucose and blood liquid, and it is of important clinical significance.