摘要
A型肉毒毒素(BTX-A)最早应用于眼部肌肉痉挛,发现具有舒展皮肤去除皱纹的功效,目前广泛用于面部年轻化及一些皮肤病的治疗。病理性瘢痕包括增生性瘢痕和瘢痕疙瘩,目前还没有满意的治疗方法,影响患者容貌美观并造成极大的心理困扰,严重者可影响机体的功能和日常生活。经体外和临床研究证明,BTX-A用于病理性瘢痕安全、有效,在预防和早期治疗方面有明显的优势。本文就近年来BTX-A作用于病理性瘢痕的相关机制和临床研究综述如下。
Botulinum toxin type A（ BTX-A） was first used in the treatment of ocular muscle spasm and found to have the effect of stretching the skin to remove wrinkles. Currently, BTX-A is widely used in the treatment of facial rejuvenation and some dermatological diseases.Pathological scar,including hypertrophic scars and keloids, causes great trouble to the patient＇s appearance and psychology, severe cases can affect the body＇s function and daily life. BTX-A has been used in vitro and in clinical studies for pathologic scars and has obvious advantages in prevention and early treatment. It has been proven to be safe and effective. In this paper,mechanism of BTX-A on the pathological scar and clinical studies are reviewed.
作者
杨欣欣
吴信峰
YANG Xin-xin;WU Xin-feng(Department of Plastic Surgery,Hospital for Skin Diseases,Chinese Academy of Medical Sciences,Peking Union Medical College,Nanjing 210042,Jiangsu,China)
出处
《中国美容医学》
CAS
2018年第5期150-153,共4页
Chinese Journal of Aesthetic Medicine
关键词
A型肉毒毒素
病理性瘢痕
防治
减张
综合治疗
Botulinum toxin type A
pathological scar
prevention and treatment
relaxation incision
combined treatment
