团体整合心理治疗对老年抑郁症患者临床疗效研究（英文）

A Study of The Clinical Effect and Dropout Rate of Drugs Combined with Group Integrated Psychotherapy on Elderly Patients with Depression

背景:相关研究表明团体认知行为治疗对抑郁症患者确有疗效,但存在较高脱落率的问题,本研究在于探讨团体整合心理治疗模式,在保证疗效的基础上,为减少脱落率提供新的方法。目的 :探讨团体整合心理疗法对老年抑郁症的临床疗效影响。方法 :将100例老年抑郁症患者随机分为研究组(n=50)和对照组(n=50),研究组给予常规药物治疗联合团体整合心理治疗,对照组给予常规药物治疗联合团体认知行为治疗。两组分别在治疗前、治疗2周、4周、8周末采用汉密尔顿抑郁量表(HAMD-24)及老年抑郁量表(GDS-15)进行评分。结果 :组内比较,两组治疗后的HAMD总分和GDS总分均低于治疗前,且差异具有统计学意义(F=102.50,p=0.001;F=55.94, p<0.001);组间比较,两组的HAMD总分在治疗后4周、8周末比较差异均有统计学意义(F=3.82,p=0.021);两组的GDS总分在治疗后2周、4周、8周比较异常均有统计学意义(F=4.49,p=0.009);研究组脱落7例,对照组脱落16例,脱落率差异有统计学意义(x^2=4.57, p=0.032)。结论 :药物治疗联合团体整合心理疗法可显著提高老年抑郁症患者临床疗效,改善患者治疗依从性,减少治疗脱落率。

Background： Relevant studies have shown that group cognitive behavioral therapy is effective in treating patients with depressive disorder, but the dropout rate is high. The present study is aimed to explore the patterns of integrated group psychotherapy. Aims： This study investigated the clinical effects of integrated group psychotherapy for elderly patients with senile depression. Methods： One hundred elderly patients with senile depression were divided into the experiment group （n=50） and the control group （n=50） randomly. The experiment group was given regular pharmacological treatments combined with integrated group psychotherapy, while the control group was given regular pharmacological treatments combined with integrated group cognitive behavioral therapy. These two groups were assessed with the Hamilton Depression Scale （HAMD-24） and Geriatric Depression Scale （GDS-15） before the study and at two weeks, four weeks and eight weeks after the treatments. Results： According to the comparisons within these two groups, it was found that the HAMD and GDS total scores before treatments were all significantly higher than those after treatments （F=102.50, p=0.001; F=55.94, p〈0.001）. We found that the HAMD total scores after four weeks and eight weeks were significantly different between the two groups （F=3.82, p=0.021）. The differences between two groups＇ GDS total scores after two weeks, four weeks and eight weeks were also significantly different （F=4.49, p=0.009）. Seven cases dropped out in the experiment group, while sixteen cases dropped out in the control group. The difference of dropout rates was statistically significant （χ^2=4.57, p=0.032）. Conclusion： Medication treatments combined with the group integrated psychotherapy significantly improve the clinical effect for elderly patients with senile depression. The compliance is improved and the dropout rate declines.