PCT检验在中枢神经系统病毒和细菌感染鉴别中的应用

Application of PCT Test in Differential Diagnosis of Central Nervous System Virus and Bacterial Infection

目的:探讨血清降钙素原(PCT)检验在中枢神经系统病毒和细菌感染鉴别中的价值。方法:选取某院收治的100例中枢神经系统感染患者,根据诊断方法分为细菌感染组(n=40例)和病毒性感染组(n=60例),并选择同期住院伴有神经系统症状的非感染患者30例作为对照组,分析3组患者血清和脑脊液当中的PCT水平。结果:细菌感染组脑脊液PCT含量显著高于病毒感染组、正常对照组(P<0.05);细菌感染组血液PCT含量显著高于病毒感染组、正常对照组(P<0.05)。结论:对于中枢神经系统病毒和细菌感染,采取PCT检验有助于协助临床诊断。

Objective：To explore the value of serum procalcitonin（PCT）test in differential diagnosis of central nervous system virus and bacterial infection.Methods：100 cases of patients with central nervous system infection treated in a hospital were selected and divided into bacterial infection group（n=40 cases）and viral infection group（n=60）,and 30 non infected patients in the same period of hospitalized patients with nervous system symptoms were selected as the control group.The levels of PCT in serum and cerebrospinal fluid（CSF）were analyzed in three groups.Results：The content of PCT in cerebrospinal fluid of bacterial infection group was significantly higher than that of viral infection group and normal control group（P〈0.05）.TThe blood PCT level in bacterial infection group was significantly higher than that in viral infection group and normal control group（P〈0.05）.Conclusion：In the case of central nervous system virus and bacterial infection,the use of PCT test is helpful for clinical diagnosis.