血清D-二聚体、肿瘤组织蛋白激酶CK2β对预测宫颈癌手术患者预后的价值分析

Analysis on the Value of Serum D-Dimer and Tumor Tissue Protein Kinase CK2β in Predicting the Prognosis of Surgical Patients with Cervical Cancer

目的探讨血清D-二聚体、肿瘤组织蛋白激酶CK2β对预测宫颈癌手术患者预后的价值。方法回顾性分析146例宫颈癌手术患者的临床资料,探讨血清D-二聚体、CK2β与宫颈癌手术患者预后的相关性。结果单因素分析显示,血清D-二聚体、CK2β水平是术后3年无复发生存率的危险因素(P<0.05);多因素分析显示,血清D-二聚体、CK2β是影响宫颈癌手术患者预后的独立危险因素(P<0.05)。结论监测血清D-二聚体、CK2β水平可预测宫颈癌手术患者的预后。

Objective To explore the value of serum D-dimer and tumor tissue protein kinase CK2β in predicting the prognosis of surgical patients with cervical cancer. Methods The clinical data of 146 patients with cervical cancer were analyzed retrospectively, and the correlations between the serum D-dimer, CK2β and the prognosis of the patients with cervical cancer surgery were investigated. Results The univariate analysis showed that serum D-dimer and CK2β were risk factors affecting three-year recurrence-free survival rate（P〈0.05）;Multivariate analysis showed that serum D-dimer and CK2β were independent risk factors affecting the prognosis of patients with cervical cancer surgery（P〈0.05）. Conclusions The prognosis of patients with cervical cancer surgery can be predicted according to the levels of serum D-dimer and tumor tissue protein kinase CK2β.