缺血性脑血管病患者单侧大脑中动脉M1段狭窄程度好转的相关因素分析

The analysis of related factors for improving the degree of unilateral middle cerebral artery M1 segment stenosis in patients with ischemic cerebrovascular disease

目的探讨促进缺血性脑血管病患者单侧大脑中动脉M1段狭窄程度好转的相关因素。方法收集2013年11月~2017年11月于河北医科大学第二医院影像科行2次头部MRA检查患者的MRA资料和相关临床资料,选取资料完善并符合纳入标准的患者共271例。对比2次MRA检查结果,依据单侧大脑中动脉M1段的变化情况将患者分为好转组46例(17%)和非好转组225例(83%),通过多因素Logistic回归分析促进缺血性脑血管病患者单侧大脑中动脉M1段狭窄程度好转的相关因素。结果多因素logistics回归分析发现无血脂代谢紊乱、无吸烟史、规律抗动脉粥样硬化治疗、规律抗血小板治疗与MCA M1段狭窄好转独立相关。结论无血脂代谢紊乱、无吸烟史、规律抗动脉粥样硬化治疗、规律抗血小板治疗可能是MCA M1段狭窄好转的保护因素。

Objective To explore the related factors of improving the degree of the unilateral middle cerebral artery M1 segment stenosis in patients with ischemic cerebrovascular disease. Methods From November 2013 to November 2017,two hundred and seventy-one cases who had completed datas and met the inclusion criteria,the MRA datas and the relevant clinical datas of patients who attended department of imaging of second hospital of Hebei Medical University two times were collected. The results of two MRA imagings were compared and the cases were divided into improvement group 46 cases （17%） and non-improvement group 225 cases （83%） according to the change of middle cerebral artery M1 segment. Multivariate Logistic regression analysis was used to analyse the related factors of improving the degree of unilateral middle cerebral artery M1 segment stenosis in patients with ischemic cerebrovascular disease. Results Multivariate logistics regression analysis showed that no lipid metabolism disorder,no smoking history,regular antiarteriosclerosis therapy,regular antiplatelet therapy were independently related to the improvement of middle cerebral artery M1 segment stenosis. Conclusion No dyslipidemia,no smoking history,regular antiarteriosclerosis therapy,and regular antiplatelet therapy may be the protective factors for the improvement of middle cerebral artery M1 segment.