愈梗通瘀汤对冠心病患者PCI术后MACE发生率及生存质量的影响

Effect of Yugeng Tongyu decoction on the incidences of MACE and quality of life of patients with coronary heart disease after PCI

目的探究愈梗通瘀汤对冠心病患者冠状动脉介入(PCI)手术后主要心血管不良事件(MACE)发生率与生存质量的影响。方法选取96例行PCI术的冠心病患者随机分为西医组(48例,常规西药治疗)与联合组(48例,常规西药治疗+愈梗通瘀汤)。比较两组患者不同时间点生存质量评分、MACE发生率。结果两组术前生存质量评分差异不明显(P>0.05);出院时两组生存质量评分均提升,且联合组显著高于西医组(P<0.05);与术前、出院时比较,两组术后6个月生存质量评分均提升,且联合组显著高于西医组(P<0.05);联合组MACE发生率明显比西医组低(P<0.05)。结论愈梗通瘀汤可降低冠心病患者PCI术后MACE发生率,并改善患者生存质量。

Objective To investigate the effect of Yugeng Tongyu decoction on major adverse cardiovascular events（MACE） and quality of life after percutaneous coronary intervention （PCI） in patients with coronary heart disease.Methods Ninety-six patients with coronary heart disease who underwent PCI were selected and randomly divided intowestern medicine group （48 cases, conventional western medicine treatment） and combination group （48 cases,conventional western medicine treatment and Yugeng Tongyu decoction）. The quality of life scores at different momentsand the incidences of MACE were compared between the two groups. Results There were no significant differences inquality of life scores before operation between the two groups （P〉0.05）; the quality of life scores in the two groupsmarkedly improved at discharge, and that in the combination group was significantly higher than the western medicinegroup （P〈0.05）. Compared with preoperative and discharge, the scores of quality of life in the two groups markedlyimproved at 6 months after surgery, and that in the combination group was significantly higher than the western medicinegroup （P〈0.05）. The incidence of MACE in the combination group was significantly lower than that of the westernmedicine group（P〈0.05）. Conclusion Yugeng Tongyu decoction can reduce the incidence of MACE after PCI in patientswith coronary heart disease, and improve the quality of life of patients.