立体定向适形放射治疗体部恶性肿瘤的临床分析

Stereotactic Conformal Radiotherapy of Body Tumors

目的:对62例体部恶性肿瘤实行立体定向适形放射治疗,并作临床分析。方法:自1997年5月至2001年5月治疗62例颅外肿瘤(89个病变部位),并进行了随访。肿瘤的临床靶体积(CTV)为0.2～254.2cm3(平均为28.7cm3),计划靶体积处方剂量为3～12Gy(平均5.38Gy),分3～10次照射。结果:治疗过程中无1例死亡。患者一般状况评分(KPS评分):治疗前l0～90分(平均60分),治疗后20～100分(平均82分)。近期疗效按实体瘤疗效标准:完全缓解(CR)6例,部分缓解(PR)34例,无变化(NC)15例,进展(PD)7例,肿瘤控制有效率为64.5%。结论:立体定向适形放射治疗颅外肿瘤有较好疗效。

Objective:To evaluate the effect of stereotactic conformal radiotherapy(SRT)of body tumors.Methods:Sixty-two patients with body tumors underwent SRT from May1997to May2001.The clinical target volume (CTV)ranged from0.2to254.2cm3with a mean dosage of28.7cm3,the irradiation dose to the Planning Target Volume (PTV)was3～12Gy (mean5.38Gy)fraction which was applied for3～10times.Results:No patient died during treatment.KPS score ranged from10to90(mean60)before treatment,and20to100(mean82)after treatment.The immediate curative effect showed CR6cases,PR34cases unchanged15cases,deteriorated7cases and tumor control rate64.5%.Conclusion:Stereotactic conformal radiotherapy is an effec-tive method in treating body tumors.