甲状腺结节的超声造影分析

Analysis of thyroid nodules by contrast-enhanced ultrasound

目的:探讨甲状腺良恶性结节的超声造影表现及其鉴别诊断价值。方法:回顾性分析69例甲状腺结节患者(共计69个结节)超声造影表现,其中恶性结节33个,良性结节36个,对比观察甲状腺良恶性结节超声造影增强模式,总结甲状腺结节超声造影表现。评价指标包括造影剂进入结节的快慢、结节增强程度、结节强化是否均匀以及造影剂廓清时间。结果:甲状腺良恶性结节在结节增强程度、结节强化是否均匀以及造影剂廓清时间3个方面的差异均有统计学意义(χ2=48.45、48.98、45.22,P<0.01)。恶性结节以"快进快出、不均匀低增强"为主,良性结节以"快进慢出、均匀高增强"为主。结论:甲状腺良恶性结节的超声造影表现有一定特异性,在鉴别诊断中有重要临床价值。

Objective： This study aimed to investigate the contrast-enhanced ultrasound（CEUS） features of thyroid nodules and to evaluate its value in differential diagnosis of benign and malignant thyroid nodules. Methods： A retrospectively analysis of CEUS features of 69 patients with 69 thyroid nodules（33 malignant and 36 benign） was conducted. CEUS performance of thyroid nodules was observed and the evaluation indicators included the speed of contrast agent entering the nodules, enhancement degree, enhancement homogeneity and clearance time of contrast agent. Results： There were statistical significances in enhancement degree, enhancement homogeneity and clearance time of contrast agent（χ^2=48.45, 48.98, 45.22, P〈0.01）. The CEUS features of malignant thyroid were mainly ＂fast in fast out＂ and ＂low uneven enhancement＂, and of benign thyroid were ＂fast in slow out＂ and ＂high even enhancement＂. Conclusion： There are significant differences in CEUS features between benign and malignant thyroid nodules. So CEUS has important clinical value in the differential diagnosis of them.