帕罗西汀对脑梗死所致抑郁、激惹及焦虑症状的疗效探析

The Effect of Paroxetine on Depression, Irritability and Anxiety Caused by Cerebral Infarction

目的探讨帕罗西汀应用于脑梗死所致抑郁、激惹及焦虑症状的临床疗效分析。方法选取2012年1月至2016年11月我院收治的356例脑梗死引发的抑郁、焦虑患者,采用随机数字法分为对照组178例与观察组178例;对照组给予及硫酸倍他司汀进行治疗,观察组在对照组基础上给予帕罗西汀治疗,对比两组患者焦虑与抑郁情况。结果观察组HAMA与HAMD-17评分显然高于对照组(P<0.05)。结论临床中采用帕罗西汀治疗脑梗死引发的抑郁、焦虑患者效果显著,可有效改善患者不良情绪,值得临床推广。

Objective To study the clinical efficacy analysis of the symptoms of depression, irritability and anxiety in paroxetine. Methods The number of depression and anxiety caused by 356 cases of cerebral infarction from January 2012 to November 2016 were divided into a control group of 178 and the observation group 178. The control group was treated with sulfuric acid betastin, and the group was given paroxetine treatment based on the control group, compared to the anxiety and depression in both groups. Results The observed group HAMA and hamd-17 were significantly higher than the control group（P〈0.05）. Conclusion The clinical treatment of cerebral infarction with paroxetine caused by the effect of patients with depression, anxiety, which can effectively improve bad mood, worth clinical promotion.