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不同含铂双药方案治疗晚期肺腺癌患者的临床疗效观察

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摘要 目的探讨不同含铂双药方案治疗晚期肺腺癌患者的临床疗效。方法在医院2015年7月至2016年2月诊治的晚期肺腺癌患者中抽取74例作研究对象,根据随机抽签原则分成两组,培美曲赛组(n=37)采取培美曲赛联合顺铂方案,紫杉醇组(n=37)应用紫杉醇联合顺铂方案,对比两组患者治疗后疾病控制率以及不良反应发生率。结果 (1)培美曲赛组患者疾病控制率是81.08%,紫杉醇组患者疾病控制率是75.68%,其对比无统计学差异(P>0.05);(2)培美曲赛组患者白细胞减少发生率、神经毒性发生率、脱发发生率均低于紫杉醇组(P<0.05或P<0.01)。结论紫杉醇联合铂类药物、培美曲赛联合铂类药物用于晚期肺腺癌患者治疗中的临床效果相当,均为高效化疗方案,而后者安全性更高,可借鉴。
作者 张冬梅
出处 《中国医药指南》 2018年第14期140-141,共2页 Guide of China Medicine
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