文化相适应的修订后认知行为治疗对抑郁症患者临床疗效的影响

The Effect of Clinical Response of Culturally Adapted Cognitive and Behavior Therapy(CBT) for Depressive Patients

目的研究与文化相适应的修订后认知行为治疗(CBT)对抑郁症患者的临床疗效的影响。方法将64例抑郁症患者随机分为研究组和对照组,分别给予根据中国文化修订后的CBT治疗和经典的CBT治疗。使用汉密尔顿抑郁量表(HAMD-17),焦虑自评量表(SAS)分别在患者治疗前与治疗6周后进行评分,对比两组的疗效差异。结果研究组和对照组在治疗前后HAMD总分[(24.09±2.26)VS(8.97±3.75),(23.75±2.82)VS(14.88±3.73)]和SAS总标准分[(67.91±4.43)VS(29.44±6.40),(68.22±4.65)VS(43.59±6.17))]均有统计学差异,两组患者在治疗6周后HAMD[(8.97±3.75)VS(14.88±3.73)]和SAS[(29.44±6.40)VS(43.59±6.17)]评分均有统计学差异。研究组和对照组在治疗6周后的完全缓解率有统计学差异(P<0.05)。结论两种方法治疗抑郁症均有明显疗效,文化相适应的修订后的CBT治疗组疗效优于经典CBT治疗组。

Objective To study the effect of clinical response of culturally adapted Cognitive and Behavior Therapy（CBT） for depressive patients. Methods64 depressive patients were randomly divided into study group and control group and treated with culturally adapted CBT and classic CBT separately. Two groups were rated by Hamilton Depression Scale（HAMD） and Self-rating Anxiety Scale（SAS） before treatment and after 6 weeks of treatment separately. The difference of treatment response was compared. Results There are statistically difference on the total score of HAMD [（24.09±2.26）VS（8.97±3.75）,（23.75±2.82）VS（14.88±3.73）] and the total standard score of SAS [（67.91±4.43）VS（29.44±6.40）,（68.22±4.65）VS（43.59±6.17）] of both study group and control group before and after 6 weeks of treatment. There was a statistically difference in the rate of complete remission between the study group and the control group after 6 weeks of treatment（P〈0.05）. Conclusion Both of the two methods have significant clinical response on depression. The clinical response of the culturally adapted CBT group is better than that of the classic CBT treatment group.