缬沙坦联合氨氯地平治疗社区老年原发高血压合并糖尿病的疗效观察

Observation of Valsartan Combined with Amlodipine in the Treatment of Elderly Primary Hypertension and Diabetes in the Community

目的探讨缬沙坦联合氨氯地平治疗社区老年原发高血压合并糖尿病的临床效果。方法选择老年高血压合并糖尿病患者60例,随机分为对照组和观察组,对照组给予氨氯地平治疗,观察组给予缬沙坦和氨氯地平治疗。观察组两组降压效果,测定治疗前后的血尿酸和空腹血糖水平。结果观察组降压效果总有效率高于对照组,差异有统计学意义(P<0.05)。观察组治疗后空腹血糖和血尿酸水平分别低于对照组治疗后空腹血糖和血尿酸水平,差异有统计学意义(P<0.05)。结论缬沙坦联合氨氯地平治疗社区老年原发性高血压合并糖尿病效果显著,降压效果显著,同时有助于控制血糖。

Objective To explore the clinical effect of valsartan combined with amlodipine in the treatment of elderly primary hypertension and diabetes in the community. Methods 60 elderly patients with hypertension and diabetes were randomly divided into control group and observation group. The control group was treated with amlodipine, and the observation group was treated with valsartan and amlodipine. The effect of blood pressure on blood uric acid and fasting blood glucose before and after treatment were measured in the two groups. Results The total effective rate of blood pressure in the observation group was higher than that of the control group, and the difference was statistically significant（P〈0.05）. The fasting blood glucose and serum uric acid level in the observation group were lower than those in the control group after treatment, the difference was statistically significant（P〈0.05）. Conclusion Valsartan combined with amlodipine is effective in the treatment of elderly patients with essential hypertension and diabetes mellitus.