白色念珠菌引起抗菌药物相关性腹泻的临床检验特点分析

Analysis of Clinical Test Features of Antimicrobial-associated Diarrhea Caused by Candida Albicans

目的探讨白色念珠菌引起抗菌药物相关性腹泻的临床检验特点。方法选取2015年6月至2016年7月武警边防总医院收治的抗菌药物相关性腹泻患者108例,采取回顾研究法,对108例患者粪便样本按照细菌培养法进行检测评估,发现54例患者感染白色念珠菌分为研究组,另外54例非白色念珠菌感染患者为对照组,对两组患者生化指数变化状况进行对比。结果研究组患者血钠、血钾及空腹血糖水平明显高于对照组(P<0.05),研究组患者测试清蛋白结果明显低于对照组(P<0.05)。结论白色念珠菌引起抗菌药物相关性腹泻相比其他菌群导致患者腹泻症状严重,另外采用粪便培养检验方式检出率高,能为治疗提供有效依据,有助于预防及治疗白色念珠菌引起抗菌药物相关性腹泻,防治抗菌药物滥用情况出现率。

Objective To study the clinical characteristics of Candida albicans-induced diarrhea-related diarrhea. Methods A total of 108 patients with diarrhea associated with antimicrobial drug-related diarrhea were enrolled in the hospital from June 2015 to July 2016.A retrospective study was conducted.Fifty-four patients were found to be infected with white rosary And 54 cases of non-Candida albicans infection were used as control group.The changes of biochemical index were compared between the two groups.Results The levels of serum sodium, serum potassium and fasting blood glucose in the study group were significantly higher than those in the control group （P〈0.05）. The albumin was significantly lower in the study group than in the control group （P〈0.05）. Conclusion Candida albicans causes antibacterial drug-related diarrhea compared with other flora leading to severe symptoms of diarrhea in patients with the use of fecal culture test method detection rate is high, can provide effective basis for the treatment.