肉桂醛选择性加氢的研究进展

Research Progress on Selective Hydrogenationof Cinnamaldehyde

肉桂醛(CAL)是α,β-不饱和醛具有代表性的物质,其C=O加氢产物是重要的医药、涂料、香料等精细化工产品中的中间体,用途广泛、经济价值高。传统的用于羰基化合物选择性加氢方法有催化加氢和催化氢转移两种途径。肉桂醛分子中同时含有C=C、C=O、苯环三种不饱和键,从热力学上讲更易对C=C键选择性加氢,导致对肉桂醇的选择性较低。如何有效实现C=O双键活化,降低其加氢反应的能垒,一直是肉桂醛选择性加氢生成肉桂醇(COL)的关键性难题。

Cinnamaldehyde（ CAL） is a representative substance of α,β-unsaturated aldehydes. Its C = O hydrogenation products are important intermediates in fine chemicals such as medicines,coatings,and perfumes. They are widely used and have high economic value. The traditional methods for selective hydrogenation of carbonyl compounds include catalytic hydrogenation and catalytic hydrogen transfer. Cinnamaldehyde contains three kinds of unsaturated bonds： C = C,C = O and benzene ring,which is thermodynamically easier to selectively hydrogenation of C = C bond,resulting in lower selectivity to cinnamyl alcohol. How to effectively realize the activation of the C = O double bond and reduce the energy barrier of its hydrogenation reaction has been a fundamental problem in the selective hydrogenation of Cinnamaldehyde to cinnamyl alcohol（ COL）.