曲马多镇痛对术后恶心、呕吐的影响

The influence of tramadol postoperative analgesia on postoperative nausea and vomiting

目的 :观察曲马多术后镇痛对术后恶心、呕吐的影响。方法 :135例腹部手术患者随机分为 :A组 (n =4 5 ) ,术后不用硬膜外镇痛 ;B组 (n =4 5 ) ,用硬膜外镇痛 ,不用恩丹西酮 ;C组 (n =4 5 ) ,硬膜外镇痛加恩丹西酮。比较B、C两组对术后恶心、呕吐的影响。结果 :A、B两组术后恶心、呕吐的发生差异无显著性 (P >0 .0 5 ) ,C组术后恶心、呕吐的发生较A、B组显著降低 (P<0 .0 0 5 ) ,B、C组镇痛效果差异无显著性 (P >0 .0 5 )。结论 :在腹部手术中曲马多硬膜外镇痛不增加术后恶心、呕吐发生率 ,硬膜外镇痛中加入恩丹西酮 ,可显著降低术后恶心、呕吐的发生。

Objective:To investigate the influence of tramadol postoperative analgesia on postoperative nausea and vomiting.Methods:One hundred and thirty five ASA Ⅰ to Ⅱ patients who had undergone abdominal operation were divided into 3 groups.Group A(45 patients) didn't receive any postoperative epidural analgesia.Group B(45 patients) received postoperative epidural analgesia without ondansetron.Group C(45 patients) received postoperative epidural analgesia plus ondansetron.Results:There was no significant difference between group A and B in the occurrence of postoperative nausea and vomiting( P >0.05).The occurrence of postoperative nausea and vomiting in group C was significantly lower than that in group A and B( P <0.005).There was no significant difference between group B and C in the effect of postoperative analgesia( P >0.05).Conclusions:In the abdominal operation,the postoperative epidural analgesia tramadol does not increase the occurrence of postoperative nausea and vomiting.The occurrence of postoperative nausea and vomiting can be decreased when ondansetron is added to the postoperative epidural analgesia liquid.