减轻应激训练对肝癌介入治疗患者创伤后应激反应及情绪的影响

Effects of stress training on post-traumatic stress response and emotion in patients with hepatocellular carcinoma after interventional therapy

目的:分析减轻应激训练对肝癌介入治疗患者创伤后的应激反应水平以及患者情绪的影响。方法:选择2016年1月至2017年7月在我院肝胆外科进行介入治疗的140例原发性肝癌患者,依据患者就诊时的ID号码采用简单随机分组的方式将其分为研究组和对照组,每组各70例,两组患者均给予术后常规一般护理措施、抗炎、补液等对症治疗及相关健康教育等,而研究组患者在以上基础上再给予减轻应激训练干预,利用PSSH量表、LOT-R量表对患者干预前后的应激反应水平和乐观倾向进行比较并分析干预前后两组患者CRP、HIF-1α等炎性因子的变化。结果:两组患者治疗干预前在应激总分上比较,差异无统计学意义(P>0.05)。研究组患者给予减轻应激训练后应激总分明显低于对照组患者(P<0.05);干预前两组患者在乐观倾向评分上比较,差异无统计学意义(P>0.05),给予干预后两组患者的评分均呈现上升趋势,研究组明显优于对照组(P<0.05);结果显示,研究组干预后患者VEGF、HIF-1α及CRP等明显低于对照组(P<0.05)。结论:采用减轻应激训练对于降低肝癌介入治疗患者创伤后应激反应和提高患者积极乐观的情绪效果显著,有利于患者病情的恢复、改善患者预后及提高患者生活质量。

Objective：To understand the effect of stress-relieving training on the level of stress response in patients with hepatocellular carcinoma after interventional therapy and emotion of patients.Methods：A total of 140 patients with primary hepatocellular carcinoma were enrolled in the hospital from January 2016 to July 2017，and the ID numbers were divided into the research group and the control group according to the random number，70 cases in each group，the two groups of patients were given routine general care measures，anti-inflammatory，rehydration and other symptomatic treatment and related health education，and the research group of patients on the basis of the above to reduce stress training intervention，the use of PSSH scale and LOT-R scale were used to analyze the level of stress response and optimism before and after intervention.Results：There was no significant difference in the total score of stress between the two groups of patients before treatment intervention （P〉0.05）.The stress score of the research group was significantly lower than that of the control group after giving stress reduction training（P＜0.05）.There was no significant difference in optimism score between the two groups before intervention（P＞0.05）.After intervention,the scores of the two groups increased,and the research group was significantly better than the control group（P＜0.05）.The VEGF,HIF-1α and CRP levels in the research group after intervention were significantly lower than those in the control group（P＜0.05）.Conclusion：The effect of stress reduction training on reducing the stress level of patients with HCC after traumatic therapy and the positive and optimistic personality of patients is very important，which is beneficial to the recovery of patients＇ condition，improvement of prognosis and improvement of quality of life.