内镜联合药物治疗肝硬化食管胃底静脉曲张破裂出血的效果

Effect of endoscopic combined drug treatment of hemorrhage of esophageal variceal rupture in liver cirrhosis

目的探讨肝硬化食管胃底静脉曲张破裂出血应用内镜联合药物诊治的效果。方法选取2014年1月~2017年8月来我院救治的肝硬化食管胃底静脉曲张患者150例,随机分为对照组和观察组,每组各75例。对照组行常规治疗,观察组行内镜联合药物的诊断治疗。详细记录并比较分析两组的治疗依从性,首次出血发生率和再出血发生率。结果观察组治疗依从性和满意度明显高于对照组,差异有统计学意义(P<0.05);观察组首次出血和再次出血发生率明显低于对照组,差异有统计学意义(P<0.05)。结论对肝硬化而导致食管胃底静脉曲张破裂出血患者应用内镜联合药物诊治的方式,其止血性更佳,再出血率更低,值得临床推广使用。

Objective To explore the effect of endoscopic diagnosis and treatment of esophagogastric variceal bleeding with cirrhosis. Methods A total of 150 patients in our hospital for treatment of cirrhosis esophageal varices were slected from January 2014 to August 2017, and were randomly divided into control group and observation group, 75 cases in each group. Patients in the control group were treated with routine treatment, patients in the observation group were diagnosed and treated by endoscopic combined drug. The treatment compliance, the first bleeding rate and the incidence of rebleeding were recorded and compared between two groups. Results The treatment compliance and satisfaction in observation group with patients were significantly higher than those in the control group, the differences were statistically significant（P〈0.05）. The incidence of bleeding and rebleeding in the observation group were significantly lower than those in the control group, the differences were statistically significant（P〈0.05）. Conclusion For patients with esophagogastric variceal rupture and bleeding caused by cirrhosis, the combination of endoscopy and drug is better than conventional methods, and it has better hemostasis and lower rebleeding rate, so it is worthy of clinical promotion.