产妇行产前C反应蛋白及甲状腺功能检测的临床应用价值

Clinical application value of prenatal C reaction protein and thyroid function detection

目的分析研讨产妇行产前常规检查与C反应蛋白(CRP)及甲状腺功能检测的临床应用价值。方法随机从2015年12月~2017年5月来我院接受产前检查的产妇中,抽取160例产妇纳入本研究,均接受常规性产前检查联合CRP及甲状腺功能检测,根据结果分为单纯CRP水平异常组、单纯甲状腺功能异常组、CRP与甲状腺功能同时存在异常的合并异常组及两指标均正常的对照组,每组各40例。对比各组产妇和胎儿状况,并分析。结果对比两组新生儿异常状况,包含死胎、新生儿窒息、新生儿畸形等,合并异常组的新生儿异常率为20.00%,高于单纯CRP异常组的15.00%、单纯甲状腺功能异常组的8.00%、对照组的1.25%,差异有统计学意义(P<0.05)。单纯CRP异常组为15.00%,高于单纯甲状腺功能异常组的8.00%、对照组的1.25%,差异有统计学意义(P<0.05);单纯甲状腺功能异常组8.00%,高于对照组的1.25%,差异有统计学意义(P<0.05)。结论建议产妇产前常规检查时,需接受CRP及甲状腺功能检测,以便及时发现产妇是否存在高危妊娠因素,采取相应干预措施,进一步确保母婴安全性。

Objective To analyze and discuss the clinical application value of routine prenatal examination combined with C reaction protein（CRP） and thyroid function detection in parturients. Methods A total of 160 cases of parturients and who received prenatal examination in our hospital from December 2015 to May 2017 were randomly included into the discussion, and were received routine prenatal examination combined with CRP and thyroid function detection. And were grouped according to the results, which the simple CRP level abnormal group, the simple thyroid dysfunction group,abnormal combination of abnormal CRP and thyroid function of combined abnormal group, the control group with two normal indexes, 40 cases in each group. Then, the status of parturients and foetuses between each group were compared and analyzed. Results The condition of two groups of newborns were compared, including stillbirth, asphyxia of the newborn, malformation of the newborn and so on. And the incidence of combined abnormal group was 20.00%, which was higher than that in the simple CRP group of 15.00%, simple thyroid dysfunction abnormal group of 8.00% and control group of 1.25%, respectively, and the difference was statistically significant（P〈0.05）. The simple CRP abnormal group was 15.00%. which was higher than that the simple thyroid dysfunction group of 8.00% and the control group of1.25%, the difference was statistically significant（P〈0.05）. The simple thyroid dysfunction group was 8.00%, which was higher than that in the control group of 1.25%, and the difference was statistically significant（P〈0.05）. Conclusion It is suggested that the parturient should receive CRP and thyroid function detection when receiving routine prenatal examination, which in order to find out whether the pregnant women have the high risk pregnancy factors in time, and it is beneficial effect on the adoption of corresponding interventions, and to further ensure the safety of mother and child.