中西医结合治疗慢性乙型肝炎肝纤维化及早期肝硬化的效果分析

Effect of Traditional Chinese Medicine Combined with Western Medicine in Treating Chronic Hepatitis B Liver Fibrosis and Early Liver Cirrhosis

目的探讨中西医结合治疗慢性乙型肝炎肝纤维化及早期肝硬化的效果。方法方便选取2017年1—12月收治的36例慢性乙型肝炎肝纤维化及早期肝硬化患者,以数字表法分组。对照组采用单纯西医方法进行治疗,观察组则给予中西医结合方案进行治疗。比较两组慢性乙型肝炎肝纤维化及早期肝硬化治疗效果;治疗前后肝功能水平和指标;干预前后患者肝纤维化水平和指标;肝区疼痛消失时间、肝肿大消失时间、腹胀消失时间。结果观察组慢性乙型肝炎肝纤维化及早期肝硬化治疗效果高于对照组[17例(94.44%)vs 11例(61.11%)](χ~2=10.946,P<0.05);干预前两组肝功能水平和指标相近(P>0.05);干预后观察组肝功能水平和指标优于对照组(P<0.05)。干预前两组肝纤维化水平和指标相近(P>0.05);干预后观察组肝纤维化水平和指标优于对照组(P<0.05)。观察组肝区疼痛消失时间、肝肿大消失时间、腹胀消失时间(9.51±1.41)、(8.21±1.61)、(8.13±1.21)周短于对照组(t=8.292、9.077、7.746,P<0.05)。结论中西医结合治疗慢性乙型肝炎肝纤维化及早期肝硬化的效果确切,可有效改善肝功能,延缓肝硬化进程,加速症状消失,缩短疗程,值得推广。

Objective This paper tries to investigate the effect of integrated traditional Chinese and western medicine in the treatment of chronic hepatitis B with hepatic fibrosis and early cirrhosis. Methods From January to December 2017, 36 patients with chronic hepatitis B liver fibrosis and early liver cirrhosis were convenient divided into groups according to the digital table. The control group was treated with western medicine only, while the observation group was treated with integrated traditional Chinese and western medicine. The effect of treatment on liver fibrosis and early cirrhosis in patients with chronic hepatitis B were compared between the two groups. The level of liver function and index before and after treatment,the level of hepatic fibrosis and the index of liver fibrosis before and after intervention, the disappearance time of liver pain,disappearance of hepatomegaly, disappearance of bloating. Results The observation group of chronic hepatitis B liver fibrosis and early liver cirrhosis treatment effect higher than the control group [17 cases（94.44%） vs 11 cases（61.11%）]（χ2=10.946, P 〉0.05）; before the intervention the liver function levels and indicators are similar（P〈0.05） After the intervention,the liver function and the index of the observation group were better than the control group（P〉0.05）. The level of liver fibrosis and the indexes were similar between the two groups before intervention（P〈0.05）. After intervention, the level and index of liver fibrosis in the observation group were better than those in the control group（P〈0.05）. The disappearance time of hepatic pain, disappearance time of hepatomegaly, and disappearance time of abdominal distension in the observation group were（9.51±1.41）,（8.21±1.61）, and（8.13±1.21）weeks, which were shorter than those in the control group（t=8.292,9.077,7.746, P〈0.05）. Conclusion Integrative Chinese and Western medicine treatment of chronic hepatitis B liver fibrosis and early cirrhosis are of the exact effect, can effectively improve liver function, delay the process of liver cirrhosis, accelerate the disappearance of symptoms, shorten the course of treatment, so it is worth promoting.