对贲门失弛缓症患者实施放置食管支架治疗的临床治疗作用研究

Clinical Study of Treatment of Esophageal Stent Placement in Patients with Achalasia

目的研究对贲门失弛缓症患者实施放置食管支架治疗的临床治疗作用。方法方便选择2012年9月—2017年9月期间接受治疗的120例贲门失弛缓症患者为对象,采用电脑随机抽取的方式将患者分为两组,每组60例,对照组使用气囊扩张的方式,观察组则应用放置食管支架治疗的方式,对比两组患者治疗效果、恢复指标、并发症发生率以及复发率。结果观察组患者症状缓解时间(3.95±1.02)d、症状消失时间(7.31±2.13)d、治愈时间(13.52±2.56)d显著低于对照组(6.23±1.12)d、(11.53±2.36)d、(17.65±4.33)d,观察组总症状评分(0.86±0.74)分、钡餐宽度(1.07±0.91)cm显著低于对照组(1.91±1.03)分、(2.83±1.32)cm,钡餐高度(6.89±1.57)cm显著高于对照组(6.03±1.36)cm,观察组患者并发症发生率6.67%显著低于对照组26.67%(P<0.05)。结论对贲门失弛缓症患者实施放置食管支架治疗,与常规气囊扩充治疗比较,整体效果较好,可降低并发症发生率,提升括约肌功能,改善临床各项指标,降低治疗后的复发率,值得在临床范围内推广使用。

Objective This paper tries to study the clinical therapeutic effect of esophageal stent placement in patients with achalasia. Methods A total of 120 patients with achalasia who were treated during the period from September 2012 to September 2017 were convenient selected. The patients were randomly divided into two groups with 60 patients in each group. The control group used balloon expansion. The observation group used the placement of esophageal stents to compare the treatment effect, recovery index, complication rate, and recurrence rate between the two groups. Results The time of symptom remission（3.95±1.02）d, symptom disappearance（7.31±2.13）d, and cure time（13.52±2.56）d were significantly lower in the observation group than in the control group（6.23 ±1.12）d,（6.23 ±1.12）d,（17.65±4.33）days, the total symptom score（0.86±0.74） points and barium meal width（1.07±0.91）cm in the observation group were significantly lower than that in the control group（1.91±1.03）points（2.83±1.32）cm, and the barium meal height was（6.89±1.57）cm was significantly higher than the control group（6.03±1.36）cm. The complication rate in the observation group was 6.67% significantly lower than the control group（26.67%）（P〈0.05）. Conclusion The placement of esophageal stents in patients with achalasia has a better overall effect compared with conventional balloon expansion therapy, which can reduce the incidence of complications, improve sphincter function, improve clinical indicators, and reduce the recurrence rate after treatment, which is worth of promotion in clinic.