加味补阳还五汤联合西药对脑梗死患者临床疗效

Effect of Jiawei Buyang Huanwu Decoction Combined with Western Medicine on the Clinical Effect,Blood Lipid and Hemorheology of Patients with Cerebral Infarction

目的:探讨加味补阳还五汤联合西药对脑梗死患者临床疗效、血脂以及血液流变学产生的影响。方法:选取2015年2月至2017年5月在北京中医医院顺义医院脑病科的脑梗死患者160例,采用随机数表法将患者分为对照组和观察组,每组80例。其中对照组采用常规西药进行治疗,观察组则在对照组基础上给予加味补阳还五汤,采用神经功能缺损(NIHSS)和日常生活能力(Barthel)指数分别对其治疗效果进行评分,根据所得数据分析血脂、血液流变学的变化。结果:2组患者治疗前NIHSS及Barthel指数评分差异无统计学意义(P>0.05),治疗后NIHSS评分均有所降低(P<0.05),但观察组分数明显大于对照组(P<0.05);治疗后Barthel指数评分均有所升高(P<0.05),但观察组升高程度明显大于对照组(P<0.05);2组患者在治疗前,NIHSS评分中意识、凝视、视野、面瘫、上下肢运动、语言等评分差异无统计学意义(P>0.05),治疗后2组患者各评分有所下降(P<0.05),但观察组各评分明显低于对照组,差异有统计学意义(P<0.05)。2组患者治疗前TC、TG、LDL-C水平差异无统计学意义(P>0.05),治疗后上述指标值均明显降低,且观察组降低的水平明显低于对照组(P<0.05);2组患者治疗前血液流变学水平差异无统计学意义(P>0.05),血液流变学指标数值在治疗后均有所降低,但观察组降低程度明显大于对照组,差异有统计学意义(P<0.05)。结论:加味补阳还五汤与西药联合治疗有利于改善脑梗死患者神经功能,提升其日常生活能力,同时降低患者的血脂并改善其血液流变学水平。

Objective： To observe the effect of Jiawei Buyang Huanwu decoction combined with western medicine on the clinical effect,blood lipid and hemorheology in patients with cerebral infarction.Methods： A total of 160 cases of cerebral infarction admitted to our hospital from February 2015 to May 2017 were selected and divided into control group and observation group according to the random number table method,80 cases in each group.The patients in the control group using conventional western medicine treatment,the observation group in the control group were given flavored Yang also five soup,the nerve function defect（ NIHSS）and the ability of daily life（ Barthel） assessed the therapeutic effect index of two groups of patients,and to analyze the changes of blood lipid and Hemorheology in the treatment of emergence.Results： Two groups of patients before treatment NIHSS score and Barthel index had no significant difference（ P〈0.05）,the NIHSS score of the two groups were decreased after treatment（ P〈0.05）,but the patients in the observation group was remarkably higher than that of control group（ P〈0.05 group）; two patients with Barthel index were increased after treatment,but the observation group（ P〈0.05） patients with elevated level was significantly higher than the control group（ P〈0.05）; the two groups of patients before treatment,no significant difference in NIHSS score of consciousness,gaze,vision,facial paralysis,upper limbs and lower limbs and language scores（ P〈0.05）,after treatment,the score of the two groups decreased（ P〈0.05）,but the observation group was significantly lower than the control group（ P〈0.05）,with statistical significance.Two groups of patients before treatment,TG,TC,LDL-C levels were not significantly different（ P〉0.05）,the two groups after treatment in patients with TG,TC and LDL-C levels were significantly decreased,and the observation group TG,TC and LDL-C levels were significantly lower than that of the control group（ P〈0.05）; the blood rheology level is no significant difference between two groups（ P〉0.05）,two groups of patients with blood rheology indexes were decreased after treatment,but the observation group was remarkably higher than that of control group（ P〈0.05）,with statistical significance.Conclusion： Jiawei Buyanghuanwu Decoction Combined with western medicine is beneficial to improve neurological function,improve daily life ability,reduce blood lipid and improve hemorheology in patients with cerebral infarction.