静脉自控分娩镇痛与硬膜外分娩镇痛的临床应用对比研究

Comparative Study of Clinical Application of Intravenous Analgesia and Epidural Analgesia

目的研究静脉自控镇痛和硬膜外分娩镇痛在临床上的应用价值。方法便利选择2016年2月—2017年10月该科接诊的分娩镇痛产妇104例,将之按照电脑随机双盲法进行分组:A组和B组各52例。A组实行静脉自控分娩镇痛,B组实行硬膜外分娩镇痛。分析两组不良反应的发生情况,比较镇痛起效时间等指标等。结果 A组的镇痛起效时间为(1.1±0.2)min,明显比B组的(15.6±2.1)min短,组间差异有统计学意义(t=9.764 1,P<0.05)。A组的不良反应发生率为13.46%,和B组的26.92%比较差异有统计学意义(χ2=5.621 7,P<0.05)。A组镇痛起效时和镇痛1、2 h后的VAS评分依次为(4.9±1.6)分、(4.7±1.2)分、(5.1±0.8)分,明显比B组的(2.1±1.3)分、(2.0±1.6)分、(3.9±0.7)分高,组间差异有统计学意义(t=9.764 1,9.734 9,8.1404,P<0.05)。结论采取静脉自控分娩镇痛法对分娩镇痛产妇进行干预,可有效降低不良反应发生风险,缩短镇痛起效时间。

Objective This paper tries to study the clinical value of intravenous self controlled analgesia and epidural labor analgesia. Methods 104 cases of delivery and were convenient selected from February 2016 to October 2017 for undergraduates and grouped them according to a randomized, double-blind computer method： 52 cases in group A and B. In group A,analgesia was controlled by intravenous self-administration and group B was given epidural analgesia. The incidence of adverse reactions in the two groups was analyzed and indicators such as analgesia onset time were compared. Results The onset time of analgesia in group A was（1.1±0.2） min, which was significantly shorter than that in group B（15.6±2.1） min. The difference between groups was statistically significant（t=9.764 1, P〈0.05）. The incidence of adverse reactions in group A was13.46%, which was statistically significant different from 26.92% in group B（χ2=5.621 7, P〈0.05）. The VAS scores of group A were（4.9±1.6） points,（4.7±1.2） points,（5.1±0.8） points, and significantly higher than those of group B（2.1±1.3）points at 1 hour and 2 hours after analgesia. The scores were（2.0±1.6） points and（3.9±0.7） points, with significant differences between groups（t=9.764 1,9.734 9,8.140 4, P〈0.05）. Conclusion The use of intravenous self-controlled delivery and analgesia to intervene in labored analgesia can effectively reduce the risk of adverse reactions and shorten the onset of analgesia.