三子重楼汤联合阿奇霉素治疗支原体肺炎的临床效果

Clinical effect of Sanzi Chonglou decoction combined with azithromycin in the treatment of mycoplasma pneumonia

目的观察三子重楼汤联合阿奇霉素治疗支原体肺炎的临床疗效及对血清炎性因子水平的影响。方法将我院226例支原体肺炎患者随机分为对照组和观察组,各113例。对照组采用阿奇霉素治疗,观察组在对照组的基础上给予三子重楼汤治疗。比较两组患者的临床疗效、治疗前、后炎性因子水平及患者症状体征消失时间。结果治疗后,两组患者的IL-6、TNF-α水平均显著降低,且观察组IL-6、TNF-α水平低于对照组(P<0.05)。治疗后,观察组患者的临床治疗效果明显优于对照组,观察组肺部干湿音、发热、咳嗽及喘息消失时间短于对照组(P<0.05)。结论三子重楼汤联合阿奇霉素治疗支原体肺炎疗效显著,能降低炎性因子,改善临床体征,值得临床推广使用。

Objective To observe the clinical effect of Sanzi Chonglou decoction combined with azithromycin in thetreatment of mycoplasma pneumonia. Methods A total of 226 patients with mycoplasma pneumonia were randomly dividedinto control group and observation group, with 113 cases in each group. The control group was treated with azithromycin, andthe observation group was treated with Sanzi Chonglou decoction on the basis of the control group. The clinical efficacy,levels of inflammatory factors before and after treatment and the disappeared time of symptoms and signs of the two groupswere compared. Results After treatment, the levels of IL-6 and TNF-α in the two groups significantly decreased, and those inthe observation group were lower than the control group （P〈0.05）. After treatment, the clinical treatment effect of theobservation group was significantly better than that of the control group, the disappeared time of dry and wet rales, fever,cough and breather in the observation group were shorter than those in the control group （P〈0.05）. Conclusion SanziChonglou decoction combined with azithromycin in the treatment of mycoplasma pneumonia has significant effect, and candecrease the levels of inflammatory factors, improve clinical signs, which is worthy of clinical promotion and application.