两种术式治疗早期乳腺癌的临床疗效研究

Research on Clinical Curative Effect of Two Operation Methods in Treatment of Early Breast Cancer

目的对早期乳腺癌患者采取保乳术与改良根治术治疗的临床疗效进行对比分析。方法方便选取2012年1月—2016年1月来该院诊治的早期乳腺癌患者100例进行该次相关研究,100例患者根据随机分配的原则按照每组50例分为对照组和观察组。对照组治疗方式为根治术,而观察组治疗方式为保乳术,对比分析两组不同治疗方式后的临床疗效情况。结果观察组的临床优良率94.0%、并发症发生情况8.0%以及术中出血量(259.96±18.14)m L、手术时间(158.86±6.52)min、引流量(259.36±14.67)m L等手术指标情况均要好于对照组,差异有统计学意义(P<0.05)。但两组的复发率、转移率等差异无统计学意义(P>0.05)。结论早期乳腺癌患者采取保乳术与根治术治疗均有效,但保乳术在短期疗效中更为理想,能够显著提高乳房外形优良率,手术时间短,患者出血量少,恢复快。从长期疗效来看,复发、转移的几率在两种手术中无明显差异,在严格把握适应征的情况下,首先考虑保乳术治疗。

Objective To compare and analyze the clinical curative effect of breast conserving surgery and modified radical mastectomy in treatment of patients with early breast cancer. Methods 100 cases of patients with early breast cancer admitted and treated in our hospital from January 2012 to January 2016 were selected and randomly divided into two groups with50 cases in each, the control group were treated with radical mastectomy, while the observation group were treated with breast conserving surgery, and the clinical curative effect was compared between the two groups. Results The clinical excellent and good rate, occurrence of complications, intraoperative bleeding amount, operation time and drainage amount in the observation group were respectively 94.0%, 8.0%,（259.96±18.14）m L,（158.86±6.52）min,（259.36±14.67）m L, which were better than those in the control group, and the differences were statistically significant（P〈0.05）, and the differences in the recurrence rate and transport rate between the two groups were not statistically significant（P〈0.05）. Conclusion Both the breast conserving surgery and modified radical mastectomy in treatment of patients with early breast cancer can produce an effective effect, but the short-term curative effect of breast conserving surgery is more ideal, which can obviously improve the excellent and good rate of mammary contour, with short operation time, less bleeding amount and rapid recovery, and there are no obvious differences in the recurrence rate and transfer rate, and the breast conserving surgery should be preferably considered under the condition of strictly mastering the indications.