非小细胞肺癌患者出院后口服吉非替尼治疗的延续性护理

Continuous nursing management of non-small cell lung cancer patients with oral administration of gefitinib at home

目的探讨延续性护理在非小细胞肺癌患者出院后口服吉非替尼治疗中的应用效果。方法 60例出院后在家口服吉非替尼治疗的肺癌患者随机分为观察组和对照组,各30例。对照组给予常规健康教育,观察组在对照组基础上实施院外延续性护理。比较2组患者相关健康知识掌握情况、遵医行为、不良反应发生情况。结果观察组相关健康知识掌握率(90.00%)及遵医率(93.33%)均高于对照组(60.00%,56.67%),差异有统计学意义(P<0.01)。观察组发生皮疹8例,腹泻2例,食欲下降1例。对照组发生皮疹20例,腹泻12例,食欲下降8例,口腔溃疡4例,转氨酶升高4例。结论延续性护理能够改善肺癌患者出院后口服吉非替尼的遵医行为,提高疾病认知,有利于控制不良反应。

Objective To investigate the effect of continuous nursing management of nonsmall cell lung cancer（ NSCLC） patients with oral administration of gefitinib at home. Methods Totally 60 NSCLC patients with oral administration of gefitinib at home were assigned to the observation group and the control group. Patients of both two groups received routine health education before discharge,and those in the observation group were given continuous nursing interventions. The health-related knowledge,treatment compliance and drug-induced complications were observed and compared between two groups. Results The awareness rate of health-related knowledge and treatment compliance rate were higher in the observation group than those of controls（90. 00% vs. 60. 00%,P〈0. 01; 93. 33% vs. 56. 67%,P〈0. 01）. There were 8 cases of skin rash,2 cases of diarrhea and 1 case of loss of appetite in the observation group. There were 20 cases of skin rash,12 cases of diarrhea,8 cases of loss of appetite,4 cases of canker sores and 4 cases of elevated serum transaminases levels in the control group. Conclusion The continuous nursing management is potentially effective to improve the treatment compliance of NSCLC patients with oral administration of gefitinib at home.