左半结肠癌左侧睾丸转移1例报告并文献复习

Left testicular metastasis in left colonic cancer: A case report and literature review

目的:探讨结直肠癌睾丸转移的临床特点、诊断、治疗与预后。方法:通过1例左半结肠癌左侧睾丸转移的报道,分析其临床资料并复习相关文献。结果:本例患者为30岁年轻男性,左半结肠低分化腺癌根治性术后1年余出现左侧睾丸肿胀坠痛,后经左侧睾丸根治性切除,免疫组化证实为大肠来源。结论:结直肠癌睾丸转移报道罕见,临床表现一般为睾丸肿胀或鞘膜积液等非特异性症状,诊断依靠病理学检查。治疗一般采取手术、放化疗,必要时联合分子靶向治疗等。结直肠癌睾丸转移患者确诊后平均生存时间为6~12个月。

Objective：To investigate the clinical features,diagnosis,treatment and prognosis of testicular metastasis in colorectal cancer.Methods：The clinical data of left testis metastasis in left colonic cancer were observed,and the related literature were reviewed.Results：In this case,a 30-year-old young man underwent swelling and pain of left testiclein one year after radical operation of left colonic cancer.The left testicle was resected radically,and confirmed the origin of the large intestine by immunohistochemistry results.Conclusion：Testicular metastasisin colon cancer was reported rarely.The clinical manifestations are generally testicular swelling or hydrocele and other non-specific symptoms.The final diagnosis still depends on pathological confirmation.Common therapy modalities may include surgery,radiotherapy or chemotherapy and if necessary,combined molecular targeted treatment.Patients with colon cancer with metastasis to the testes survival averaged 6~12 months from diagnosis.