四肢骨折内固定术后手术部位感染相关因素分析

Analysis of the correlation factors of the surgical site infection after limbs fracture fixation

目的:分析四肢骨折内固定术后手术部位感染相关因素。方法:收集四肢骨折行切开复位内固定手术患者152例,根据内固定术后有无手术部位感染将患者分为感染组51例和未感染组101例,对两组患者的临床资料进行组间比较,并行多因素logistic回归分析。结果:感染组和未感染组在合并基础疾病、受伤至手术时间、多处骨折、伤口污染、应用激素、手术时间、术中失血量、术后引流管留置时间、住院时间等方面差异均有统计学意义(P<0.05);多因素logistic回归分析结果显示,合并基础疾病、开放性骨折、伤口污染、应用激素、手术时间≥3 h是四肢骨折内固定术后手术部位感染的独立危险因素。结论:对于行切开复位内固定术的四肢骨折患者,应重视各种易引起术后感染的危险因素,做好防护工作,以减少感染的发生。

Objective： To analyze the relative factors of surgical site infection after limbs fracture fixation. Methods： One hundred and fifty-two cases undergone limbs fracture fixation were selected and divided into an infectious group（n=51） and a noninfectious group（n=101）. The clinical data were compared and multivariate logistic regression analysis was performed. Results： There were significant differences between the two groups in complicated with underlying diseases, time interval from injury to surgery, multiple fractures, wound contamination, hormone use, operation time, intraoperative blood loss, drainage tube indwelling time and hospital stays（P〈0.05）. Multivariate Logistic regression analysis showed that the independent risk factors of surgical site infection after limbs fracture fixation were complicated with underlying diseases, open fractures, wound contamination, hormone use and operation time ≥3 hours. Conclusion： Attention should be paid to various risk factors that may cause postoperative infection and protection should be strengthened for the patients with limb fractures undergone open reduction and internal fixation so as to reduce the incidence of infection.