妊娠早期发现的亚临床甲状腺功能减退对妊娠结局的影响分析

The impact analysis of subclinical hypothyroidism on the pregnant outcome in the first trimester of pregnancy

目的研究妊娠早期发现的亚临床甲状腺功能减退对妊娠结局的影响。方法将妊娠早期产检发现亚临床甲状腺功能减退的患者106例,随机分为左甲状腺素片治疗组与不用药观察组,各53例;选取同期产检的甲状腺功能正常的孕妇53例为对照组;对各组孕产妇的妊娠结局对比分析。结果观察组的不良妊娠结局发生率高于治疗组和对照组,差异均具统计学意义(P<0.05)。结论妊娠早期合并亚临床甲状腺功能减退会增加不良妊娠结局发生率;早期药物干预可降低不良妊娠结局发生率。

Objective To study the effect of subclinical hypothyroidism on pregnancy outcome in early pregnancy. Methods Early pregnancy prenatal examination found 106 cases of subclinical hypothyroidism patients were randomly divided into levothyroxine treatment group and study group of 53 patients without medication; thyroid function of pregnant women were selected. The 53 normal cases as control group. To analysis and compared the impact of subclinical hypothyroidism on the pregnant outcome in the first trimester of pregnancy. Results The incidence of adverse pregnancy outcomes in the study group was higher than that in the treatment group and the control group. Conclusion Subclinical hypothyroidism in early pregnancy can increase the incidence of adverse pregnancy outcomes, and early drug intervention can reduce the incidence of adverse pregnancy outcomes.outcome.