慢性支气管炎型慢性阻塞性肺疾病的治疗与预后

Treatment and prognosis of chronic bronchitis phenotype in chronic obstructive pulmonary disease

目前，慢性阻塞性肺疾病（COPD）研究的热点之一是表型研究。COPD患者在临床表现、影像学特征、病程发展和治疗反应等方面存在较大差异，表型识别不仅有助于认识这种异质性，还具有潜在的诊断和治疗意义。COPD的临床表型包括慢性支气管炎表型、肺气肿表型和急性加重表型等。本文就慢性支气管炎型COPD的治疗和预后作一简要综述。

At present, phenotypic problem is one of the focus of chronic obstructive pulmonary disease （COPD） research. COPD is a complex, multi-component, heterogeneous disease, whose clinical, functional and radiologieal presentation, therapeutic response vary greatly from patient to patient despite having a similar degree of airflow limitation. Phenotypic recognition of not only helps to recognize this heterogeneity, but also has potential diagnostic and therapeutic significance. The clinical phenotypes of COPD include chronic bronchitis phenotype, emphysema phenotype and acute exacerbation phenotype. Herein, we will descrihe current undei＇standing of chronic bronchitis in COPD, with an emphasis on recent literature.