应用改良巩膜瓣可调缝线的青光眼手术效果观察

Observation on the efficacy of application of modified scleral flap adjustable suture in glaucomasurgery

目的观察应用改良巩膜瓣可调缝线在青光眼滤过术中的效果。方法观察组：青光眼65例（65眼）采用经结膜的改良巩膜瓣可调缝线联合应用丝裂霉素C。对照组：青光眼63例（63眼），采用传统常规小梁切除术。结果术后7 d、2个月、6个月、1年的平均眼压，观察组依次为（12.1±1.8）mmHg、（13.4±2.2）mmHg、（14.3±2.3）mmHg、（14.8±1.4）mmHg；对照组依次为（13.15±1.01）mmHg、（15.11 ±0.76）mmHg、（17.34 ±0.84）mmHg、（18.62 ±0.47）mmHg（1 mmgH＝0.133 kPa）。术后7 d和2个月两组间眼压比较差异均无统计学意义（t＝1.535，1.232；P＝0.134，0.976）；术后6个月和1年两组间眼压比较差异有统计学意义（t＝0.453，0.253；P＝0.029，0.003）。结论应用改良巩膜瓣可调缝线联合丝裂霉素C治疗青光眼，术后6个月及1年仍能有效地控制眼压。

ObjectiveTo observe the efficacy of application of modified scleral flap adjustable suture in glaucoma filtering operation.MethodsAll cases with glaucoma were divided into 2 groups randomly. The observation group, 65 eyes of 65 cases received modified scleral flap adjustable suture combined with application of mitomycin-C treatment. The control group, 63 eyes of 63 cases underwent traditional trabeculectomy.ResultsThe intraocular pressure（IOP） at 7 days, 2 months, 6 months and 1 year after surgery were （12.1±1.8）mmHg, （13.4±2.2）mmHg, （14.3±2.3）mmHg, （14.8±1.4）mmHg in the observation group and（13.15±1.01）mmHg, （15.11±0.76）mmHg, （17.34±0.84）mmHg, （18.62±0.47）mmHg in the contorl group（1 mmHg=0.133 kPa）. The difference of IOP were not statistically significant between the two groups at 7 d and 2 months after operation（t=1.535, 1.232; P=0.134, 0.976）. The difference of IOP at 6 months and 1 year was statistically significant between the two groups（t=0.453, 0.253; P=0.029, 0.003）.ConclusionThe application of modifide scleral flap adjustable suture combined with mitomycin-C for the treatment of glaucoma is effective for controlling IOP at 6 and 12 months after surgery.