肺炎支原体培养法与肺炎支原体抗体检测的比较

Comparative study on Mycoplasma pneumoniae cultural method and Mycoplasma pneumoniae antibody detection

目的比较微生物快速培养(MRD)与肺炎支原体免疫球蛋白M(MP-IgM)抗体检测在诊断患儿肺炎支原体(MP)感染中的临床效果。方法选择2017年3月—12月天津市宝坻区人民医院确诊患有MP感染的148例患儿作为研究对象,根据检测方法的不同将其分为两组,其中74例患儿采用MRD法进行检测,74例患儿采用MP-IgM抗体检测法进行检测,对比两种检测方法的阳性率情况。结果 MRD法测出阳性者68例(91.89%),MP-IgM法测出阳性者58例(78.38%),MRD法的阳性率较MP-IgM法明显升高(P<0.05)。结论 MRD法与MP-IgM抗体检测法在早期MP感染的诊断中均具有较高的诊断价值,应用MRD法诊断较MP-IgM抗体检测法具有一定的优势,但两种方法各有优缺点,临床可考虑将两种方法联合应用。

Objective To compare the clinical effect between microbial rapid cultural detection（MRD） and Mycoplasma pneumoniae M（MP-IgM） antibody assay in the diagnosis of MP infection in children. Methods From March 2017 to December 2017, 148 children with MP infection in Tianjin Baodi People＇s Hospital were selected as subjects. Based on different methods of detection, they were divided into two groups, of which 74 cases were detected by MRD（MRD group）, and 74 cases were detected by MP-IgM antibody test（MP-IgM group）, then the MP positive rates of the two groups were compared. Results There were 68 positive cases in MRD group（91.89%）, and 58 positive cases in MP-IgM group（78.38%）. The positive rate in MRD group was significantly higher than that in MP-IgM group（P〈0.05）. Conclusions In the early diagnosis of MP infection in children, MRD and MP-IgM antibodies detection are of relatively high diagnostic value, and the application of MRD has certain advantages over MP-IgM antibody detection as the formal MP positive rate is higher than the latter, however, both methods had their own advantages and disadvantages, therefore they can be used in combination.