Oddi括约肌功能障碍的诊治进展

Advances on diagnosis and therapy of sphincter of Oddi dysfunction

Oddi括约肌功能障碍（SOD）是由于Oddi括约肌收缩异常，肝胰壶腹部流出受阻，胆汁、胰液反流引起的胆胰系统一系列病理生理变化的综合征。由于缺乏典型的临床症状和特异性的诊断方法，其诊断和治疗标准尚不明确。近年来，随着内镜技术和大型临床试验的开展，学界对该病的认识有了新的变化。本文就SOD的诊断、治疗等最新研究进展作一综述。

Sphincter of Oddi dysfunction （SDO） is the obstruction of ampulla of Vater, resulting from abnormality of contraction of sphincter of Oddi, which causes the reflux of bile and pancreatic juice and promotes a series of pathophysiological changes in cholangiopancreatic system. Because of lack of typi- cal clinical symptoms and specific diagnostic methods, the standards of diagnosis and therapy are still unclear. Recently, new changes happened in this field with the development of en- doscopy and large-scale clinical trials. This review summarized the latest advances on sphincter of Oddi dysfunction in recent years.