自体动静脉内瘘栓塞危险因素1:2配对条件Logistic回归分析

Logistic regression analysis on 1:2 paired condition of risk factors of autologous arteriovenous fistula embolization

目的探讨自体动静脉内瘘栓塞可能的危险因素。方法选择我院首次发生动静脉内瘘栓塞的45例患者作为病例组,并根据1:2配对条件选择内瘘功能良好的患者90例作为对照组,对可能导致自体动静脉内瘘栓塞发生的因素作单因素分析与Logistic多元回归分析。结果单因素分析表明,透析后低血压、糖尿病、血液高凝状态、高Chalrson合并症指数、透析次数多以及大剂量EPO与自体动静脉内瘘栓塞的发生有关(P<0.05),Logistic回归分析显示糖尿病、透析后低血压、血液高凝状态以及透析次数多是患者发生自体动静脉内瘘栓塞的独立危险因素。结论动静脉内瘘栓塞是多种因素综合作用的结果,应采取综合措施预防内瘘栓塞。

Objective To investigate the possible risk factors of autogenous arteriovenous fistula embolization. Methods 45 patients with arteriovenous fistula embolization in our hospital were selected as the case group. According to the 1：2 paired conditions, 90 patients with good internal fistula function were selected as the control group. Univariate analysis and Logistic multivariate regression analysis of factors that might lead to the occurrence of autogenous arteriovenous fistula embolization were carried out. Results Univariate analysis showed that post-dialysis hypotension, diabetes, hypercoagulable state, high Chalrson comorbidity index, frequent dialysis, and high dose of EPO were associated with the occurrence of autogenous arteriovenous fistula embolization （P〈0.05）. Logistic regression analysis showed that diabetes, post-dialysis hypotension, hypercoagulable state, and frequent dialysis were independent risk factors for autologous arteriovenous fistula embolization. Conclusion Arteriovenous fistula embolization is the result of a combination of multi- ple factors. Comprehensive measures should be taken to prevent internal fistula embolization.