结直肠癌患者术后改善营养不良、提高免疫力的营养支持方案研究

Study on nutrient support program for improving malnutrition and immunity in postoperative patients with colorectal cancer

目的探讨早期肠内联合肠外营养支持在结直肠癌患者术后改善营养不良、提高免疫力的临床研究。方法收集2014年1月~2017年12月间在本院确诊且行手术治疗的结直肠癌患者40例,使用随机抽签的方法分为实验组和对照组,各20例,实验组患者采用早期肠内联合肠外营养支持方案,对照组采用全肠外营养支持方案,对两组的术后营养学指标、免疫指标和炎症指标等进行统计和分析。结果术后7 d实验组营养指标水平和免疫指标水平明显高于对照组,差异具有统计学意义(P<0.05),实验组炎症指标水平CRP明显低于对照组,差异具有统计学意义(P<0.05)。结论对于结直肠癌患者术后早期肠内联合肠外营养支持方案能够快速改善患者营养不良,提高免疫力。

Objective To investigate the clinical effects of early enteral combined with parenteral nutrition support in improving malnutrition and improving immunity in postoperative patients with colorectal cancer. Methods Forty patients with eolorectal cancer who were diagnosed and underwent surgery in our hospital between January 2014 and December 2017 were divided into experimental group and control group by random drawing method, with 20 cases in each group. The experimental group was treated with enteral combined with parenteral nutrition support program, and the control group was given total parenteral nutrition support program. Postoperative nutritional indicators, immune indicators and inflammation indicators of the experimental group and the control group were statistically analyzed. Results The levels of nutritional and immune parameters of the experimental group were significantly higher than those of the control group on the 7th day after operation, and the difference was statistically significant（P〈0.05）. And the level of inflammation index CRP in the experimental group was significantly lower than that of the control group, and the difference was statistically significant （P〈0.05）. Conclusion Early enteral combined parenteral nutrition support program for patients with colorectal cancer can rapidly improve malnutrition and improve immunity.