中药治疗乳腺癌的处方特征分析及辨证思维探讨

Analysis on the prescription characteristics and discussion on the dialectical thinking of breast cancer treated by traditional Chinese medicine

目的探讨乳腺癌的辨证思想。方法收集于2015年9月~2017年5月我科住院及门诊的乳腺癌患者252例,将252病例分为7大证型,并把其所涉及226味中药根据《中药学》归纳为11类,应用描述性统计学方法进行统计分析。结果各证型间比较差异有统计学意义(P<0.01),肝郁痰凝型与其余各证型两两比较均有明显的统计学意义(P<0.005),余证型间两两比较无明显的统计学差异(P>0.05)。药物使用频次分析结果显示,使用频率在10%以上的药物共44味,总使用频次为4999次,占药物总频次的69.61%,其中以疏肝理气药、化痰散结药和补虚药为主要代表。结论乳腺癌治疗主要应用疏肝解郁法,常用理气化痰散结药。

Objective To explore the dialectical thinking of breast cancer. Methods 252 patients with breast cancer who were hospitalized and diagnosed in the outpatient clinic in our department from September 2015 to May 2017 in our department were collected. The 252 patients were divided into 7 major types. In addition, the 226 Chinese herbs involved in the study were classified into 11 categories based on the book entitled ＂Science of Chinese Traditional Medicine＂. The descriptive statistical method was applied for statistical analysis. Results The differences were statisti cally significant between the syndromes（P〈0.01 ）. There was a statistically significant difference between the type of stagnation of liver-Qi and phlegm and the remaining syndromes （P〈0.005）. There was no statistically significant differ- ence between the remaining syndromes（P〉0.05）. The frequency of drug use analysis showed that 44 drugs were used at the frequencies above 10%. The total frequency was 4999 times, accounting for 69.61% of the total frequency of drug use. Among them, the main representatives were the drugs of dispersing the liver and rectifying Qi, the drugs of reducing phlegm and resolving masses and the drugs of tonifying deficiency. Conclusion The main application of breast cancer therapy is to disperse stagnated liver Qi to relieve depression. The drugs of tonifying Qi, reducing phlegm and resolving masses should be commonly used.