142例HIV-1抗体确证结果的分布规律研究

Study on the distribution of the results of HIV-1 antibody confirmation in 142 cases

目的 探讨142例新发现的HIV抗体确证的患者确证结果的分布规律。 方法 选取2014-2017年于佛山中医院就诊并确证为HIV抗体阳性的新报告142例患者作为研究对象，对其基本资料及免疫印迹法带型进行趋势及描述性分析。 结果 （1）各年间HIV抗体检出率差异有统计学意义（ χ 增幅 =7.889， P 〈 0.005 ）；（2）男性HIV检出率（84.51％）高于女性（5.50%），差异有统计学意义（ χ 2 =34.099， P 〈0.005）；感染者主要以30～39 岁为主（76.05%）。（3）HIV住院部检出例数最高（62.68%），其次为综合门诊（34.51%），体检中心（5.63%）；住院部高发科室有骨科、肺病科和脾胃科；门诊部高发科室为男科和皮肤科。（4）gp160、gp120、p24的阳性率最高（100.00%），其次为p31、gp41、p55、p51阳性率均在90%，p17与p66的阳性率较低，分别为71.83%、42.25%。（5）不同性别和不同年龄组的WB带型显带率接近，差异均无统计学意义（ P ＞ 0.05 ）。 结论 近四年佛山中医院艾滋病疫情呈上升趋势和男性化，且为多年龄段分布。该院应对高发科室患者普遍筛查HIV抗体，并加强老年人的行为干预。

Objective ： To investigate the distribution of 142 patients with HIV-1 antibody confirmed positive. Methods： Selecting 142 patients with HIV-1 antibody positive who doctor and confirmed from January 2014 to October 2017 in TCM as the research object and then to analysis of trends and describe its basic information and immunoblotting with type. Results： （1） The HIV-1 antibody detection rate was significantly in various years （ χ 2 growth=7.889, P 〈0.005）;（2）The detection rate of the Male （84.51%） more than that of the females （5.50%）,the difference was statistically significant;HIV infection crowd is mainly concentrated in the 20 to 49 years （76.05%）.（3） Inpatient detected HIV cases highest number （62.68%）,followed by polyclinics （34.51%）,medical center （5.63%）;inpatient high sections have orthopedics,pulmonary branch and stomach Section;clinic high sections is andrology and skin Section.（4）About the positive rate,gp160,gp120and p24 was the highest （100.00%）,followed by p31,gp41,p55,p51 at 90%,a lower positive rate of p17 and p66,respectively,71.83%,42.25%.（5） WB with a positive rate of different sexes and different age groups are close and show no significant difference （ P 〉0.05）. Conclusion ： Nearly four years,HIV patients in TCM showed a positive rate of growth,was masculine,and for the distribution of multiple ages.We deal with high patient departments universal screening HIV antibody and to strengthen the elderly behavioral intervention.