分析先兆早产采用宫缩抑制剂治疗的临床疗效

Analysis of clinical efficacy of uterine contraction inhibitors for preterm labor

目的:探讨先兆早产采用宫缩抑制剂治疗的临床疗效。方法:入选本次研究患者均为本院2017年3月至2018年3月产科收治的先兆早产孕妇60例,依据不同的治疗方法分为观察组和对照组,观察组患者采用宫缩抑制剂治疗,对照组患者采用常规先兆早产治疗,观察比较两组孕妇的最终妊娠情况及保胎的成功率;两组孕妇的药物起效时间、孕期延长时间及不良反应情况。结果:两组孕妇新生儿体质量比较无显著差异(P>0.05);观察组孕妇的保胎成功率、足月分娩率均要优于对照组(P<0.05),差异具有统计学意义。观察组孕妇的药物起效时间及妊娠的延长时间均要优于对照组(P<0.05),差异具有统计学意义。观察组孕妇的不良反应发生率6.7%低于对照组孕妇的23.4%(P<0.05),差异具有统计学意义。结论:采用宫缩抑制剂治疗先兆早产的临床效果显著,本次研究采用的宫缩抑制剂硫酸镁具有起效快、不良反应少等优点,值得临床进一步研究。

Objective： To explore the clinical effect of the treatment of preterm labor using uterine contraction inhibitor. Meth- ods： This study selected patients in our hospital during March 2017 to March 2018, 60 cases of obstetric were threatened pre- mature labor, according to the different treatment methods were divided into observation group and control group, the observa- tion group were treated by tocolytic therapy, the control group was treated with conventional treatment of threatened premature pregnancy, finally compared two groups of pregnant women were observed and the success rate of miscarriage; two groups of pregnant women during pregnancy, drug onset time prolonged and adverse reaction. Results： No significant difference in birth weight of two groups （P 〉 0. 05） ; observation group of pregnant women, the success rate, term delivery rate was better than the control group （P〈0. 05）, with statistical significance. The time of drug onset and the prolongation of pregnancy in the observation group were better than those of the control group （P〈0. 05）, which had statistical significance. The incidence of adverse reaction of pregnant women in the observation group was 6.7% lower than that of the control group. The incidence of adverse reactions was 23.4%（P〈0. 05）, which was statistically significant. Conclusion： The clinical effect of uterine contraction inhibitor in the treatment of threatened premature labor is significant. The use of magnesium sulfate in this study has the advantages of quick onset and less adverse reactions. It is worthy of further clinical research and promotion.