特定耳穴贴压法治疗胃癌患者术后疼痛的临床疗效

Efficacy of specific auricular point sticking therapy for postoperative pain in patients with gastric cancer

目的探讨特定耳穴贴压法治疗胃癌患者术后疼痛的临床疗效。方法选取2016年1月至2017年1月间第二军医大学长海医院收治的104例胃癌术后患者,采用随机数表法分为治疗组(51例)和对照组(53例)。选定耳廓中的心、神门、交感、皮质下和胃5个穴位贴压,治疗组患者每日按压4次,对照组患者仅贴不按压。采用视觉模拟评分法评估两组患者术后疼痛程度,比较两组患者的γ-氨基丁酸(GABA)和β-内啡肽(β-EP)等血清学指标。结果治疗组患者术后2~5d的疼痛评分均低于对照组,差异均有统计学意义(均P<0.05);治疗组患者治疗后的GABA和β-EP均高于对照组患者,差异均有统计学意义(均P<0.05)。结论特定耳穴贴压法可有效缓解胃癌患者的术后疼痛,机制可能与上调GABA和β-EP表达有关。

Objective To observe the clinical efficacy of specific auricular point sticking therapy for postoperative pain in patients with gastric cancer. Methods From January 2016 to January 2017,104 patients with gastric cancer after operation were selected and randomly divided into a treatment group（ 51 patients） and a control group（ 53 patients）. For the treatment group,five acupoints including heart,God door,sympathetic,subcortical and stomach were selected,and the patients were pressed 4 times per day.The control groups on received auricular point sticking therapy without pressing. Postoperative pain was evaluated by numerical rating scale. Serum indexes such as gamma-aminobutyric acid（ GABA） and beta endorphin（ beta-EP） were detected and compared. Results At 2 to 5 d after the operation,the scores of pain was were lower in the treatment group than in the control group（ all P〈0. 05） and GABA and beta-EP levels were higher than in the control group（ all P〈0. 05）. Conclusion Specific auricular point sticking therapy can effectively relieve postoperative pain in gastric cancer patients,and its mechanism may be related to the up regulation of GABA and beta-EP expression.