血清HDL-C水平在老年冠心病患者冠状动脉狭窄中的检测价值研究

An Analysis of the Detective Value of the Serum HDL-C in the Elderly CHD Patients with coronary Artery Stenosis

目的探析血清高密度脂蛋白胆固醇(HDL-C)在冠心病(CHD)老年患者中的临床检测意义。方法分析2013年1月至2017年12月在我院接受治疗的192例CHD老年患者的临床资料。根据冠脉狭窄程度,将入选者分成A(轻度,70例)、B(中度,65例)、C(重度,58例)三组。比较三组患者的基线资料、治疗前后的血脂指标水平。相关性分析CHD老年患者HDL-C水平与冠脉狭窄程度的关系。结果三组患者的基线资料无明显统计学差异(P>0.05)。B、C组患者的血清TC水平明显高于A组,HDL-C水平明显低于A组(P<0.05)。TC、HDL-C是CHD患者冠脉狭窄程度的独立影响因素,其中TC与狭窄程度呈正相关,HDL-C与狭窄程度呈负相关(P<0.05)。结论血清HDL-C是CHD老年患者冠脉狭窄的独立影响因素,且HDL-C水平越低,患者冠脉狭窄程度越严重。

Objective To analyze the clinical detective value of the serum HDL-C in the elderly CHD patients with coronary artery stenosis. Methods Theclinical data of 192 elderly patients with CHD who received treatmentsin our hospital from January,2013 to December,2017 was retrospectively analyzed. Patients included were divided into three groups according to the degree of coronary artery stenosis,group A（mild,70 cases）,group B（moderate,65 cases） and group C（severe,58 cases）. The general information and the blood lipid indexes before and after treatment in three groups were compared. The relationship between the HDL-C level and the degree of coronary artery stenosis was analyzed. Results The general information in three groups had no statistical differences（P〈0. 05）. The TC levels in group B and C were significantly higher than that in group A,and the HDL-C levels in group B and C were significantly lower than that in group A（P〈0. 05）. Both TC and HDL-C were the independent risk factors of the elderly CHD patients with coronary artery stenosis（P〈0. 05）. The TC level had positive correlation with the degree of coronary artery stenosis,and the HDL-C level had negative correlation with the degree of coronary artery stenosis（P〈0. 05）.Conclusion The HDL-C level is the independent risk factor of the elderly CHD patients with coronary artery stenosis. With the lower level of HDL-C,the degree of coronary artery stenosis is more serious.